A new method of solution for the occupancy problem and its application to operon size prediction
Abstract:
The problem of estimating the expected number of transcription units containing a specific number of genes arises in the context of operon size prediction in prokaryotic genomes, where operons are defined to be transcription units containing two or more genes. It turns out that this problem is identical mathematically to the balls in urns occupancy problem in probability theory. In that problem, a fixed number of indistinguishable balls are randomly placed in a known number of distinguishable urns, subject to the restriction that no urns may remain empty, and an estimate is desired for the expected number of urns containing a specific number of balls. In this paper we present a new simple technique for solving the occupancy problem when empty urns are allowed and extend it to the case when each urn must contain the same non-zero minimum number of balls. Treating transcription units as equivalent to urns, and …
Año de publicación:
2004
Keywords:
Fuente:

Tipo de documento:
Other
Estado:
Acceso abierto
Áreas de conocimiento:
- Modelo matemático
Áreas temáticas de Dewey:
- Programación informática, programas, datos, seguridad
- Biología
- Historia, tratamiento geográfico, biografía

Objetivos de Desarrollo Sostenible:
- ODS 9: Industria, innovación e infraestructura
- ODS 17: Alianzas para lograr los objetivos
- ODS 4: Educación de calidad
