A new protection/activation strategy for the synthesis of naturally occurring and non-natural α-N-alkylamino acids

Abstract:

A new method for the preparation of N-methylamino acids and some of their derivatives starting from hexafluoroacetone protected amino acids is described. The new concept results in saving of steps compared to conventional protection/activation techniques. Protection and deprotection proceed without racemization.

Año de publicación:

1999

Keywords:

• amino acids
• Pro-Tau-chimeras
• α-N-phosphinoylmethylamino acids
• Pro-Glu-chimeras
• Hexafluoroacetone
• α-N-methylamino acids

Fuente:

scopus

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