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BLOOD GROUP B PRIMARY AND REGRAFT CANDIDATES ARE TRANSPLANTED WITH A2/A2B KIDNEYS AT THE SAME RATE SINCE A ISOAGGLUTININS REMAIN LOW: 518

Abstract:

Background: Acute Antibody-mediated rejection (AAMR) has been recognized as a major problem in ABO-incompatible (ABO-I) renal transplantation (RTX). Anti-ABO blood-type antibodies had been thought to be the main cause of AAMR. However, under the current potent immunosuppressive regimen, the role of anti-ABO blood-type antibodies for AAMR is not clearly understood. The aim of this study was to assess the impact of anti-ABO blood-type antibodies on AAMR. Methods: Fifty-eight patients who underwent ABO-I RTX at our institution between March 1999 and December 2004 under an FK-based immunosuppressive regimen were enrolled in this study. AAMR was diagnosed by biopsies within one month after transplantation in conjunction with allograft dysfunction. Morphological features of AAMR based on the Banff’05 update and other characteristic findings for AAMR previously reported, such as …

Año de publicación:

2008

Keywords:

    Fuente:

    googlegoogle

    Tipo de documento:

    Other

    Estado:

    Acceso abierto

    Áreas de conocimiento:

      Áreas temáticas:

      • Enfermedades
      • Cirugía y especialidades médicas afines

      Contribuidores:

      Daniel MurilloDaniel Murillo