Benefits of Amino Acid Balancing on Metabolism, Inflammation, and Oxidative Stress

Abstract:

Due to extensive microbial degradation in the rumen, dietary availability of key methyl donors [(eg, Methionine (MET) and choline (CHOL)] to mammary and liver is limited (Sharma and Erdman, 1989; Girard and Matte, 2005). Consequently, the mobilization of body protein in dairy cows close to calving compensates in part for this shortfall (Komaragiri and Erdman, 1997). Supplementing rumen-protected methyl donors may help fulfill the daily methyl group requirement, and possibly improve the overall production and health of dairy cows during the transition period (Zom et al., 2011; Osorio et al., 2013; Osorio et al., 2014). The availability of MET and CHOL is important for various biological functions. For instance, MET together with Lys are the most-limiting amino acids (AA) for milk synthesis (NRC, 2001). Being the only essential sulfur-containing AA, MET acts as the precursor for other sulfur-containing AA such as cysteine (Cys), homocysteine and taurine (Brosnan and Brosnan, 2006). It has been estimated in lactating goats that as much as 28% of absorbed MET could be used for CHOL synthesis (Emmanuel and Kennelly, 1984). Hence, it is thought that rumen-protected CHOL supplementation could spare MET to help cows achieve better overall performance (Hartwell et al., 2000; Pinotti, 2012). Current recommendations for duodenal supply of Lys and MET to maximize milk protein content and yield in established lactation are 7.2 and 2.4% of MP, respectively (NRC, 2001). In terms of production performance, a Lys: Met ratio close to 2.8: 1 of MP during the periparturient period by supplementing rumen-protected MET was beneficial (Osorio et al …

Año de publicación:

2016

Keywords:

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