A novel tetramer copper(I) complex containing diallylphosphine ligands: Synthesis, characterization and catalytic application in A3-coupling (Aldehyde-Amine-Alkyne) reactions

Abstract:

A novel tetrameric copper(I) complex containing tert-butyldiallylphosphine ligands, [CuCl{^tBu-P(CH<inf>2</inf>CH = CH<inf>2</inf>)<inf>2</inf>}]<inf>4</inf> (2), has been synthesized and characterized by structural and spectroscopic methods. X-ray diffraction analysis showed that 2 has a cubane-like solid structure of formula [CuCl{κ¹(P)-^tBu-P(CH<inf>2</inf>CH = CH<inf>2</inf>)<inf>2</inf>}]<inf>4</inf>. In solution, a dynamic behavior generated by the cubane ⇄ chair isomerization was detected by variable temperature NMR analysis. DFT calculations have been performed to explain the observed dynamic equilibrium in solution. The use of copper(I) complex 2 as catalyst for the synthesis of propargylamines via A³-coupling reactions has been tested. Complex 2 is capable of promoting A³-coupling reactions of both aromatic and aliphatic aldehydes with cyclic secondary amines and phenylacetylene. The reaction proceeds under mild condition and absence of solvent.

Año de publicación:

2017

Keywords:

• Tetramer cobre(I) complex
• Propargylamine
• Diallylphosphine ligands
• A -coupling reactions 3
• A3-coupling reactions

Fuente:

scopus

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