Bullous diseases

Abstract:

Bullous or bullous diseases represent a complex group of entities with common clinical features and different pathogenic mechanisms. Affecting the skin, mucous membranes and, occasionally, other epithelial tissues. Pemphigus and pemphigoid belong to the group of autoimmune bullous diseases. Despite its low incidence, have a high morbidity, so that knowledge of its main features is essential in clinical practice. Diagnosis should be made based on clinical findings, immunopathology and serology. Corticosteroids and immunosuppressive star in traditional therapeutic regimens. However, in recent years, new therapies have been developed which block the production of autoantibodies in these diseases and significantly decrease the side effects of chronic use of steroids and other immunosuppressive agents.

Año de publicación:

2014

Keywords:

• Pemphigus vulgaris
• Acantholysis
• bullous pemphigoid
• Autoimmune blistering diseases
• Immunosuppressive drugs

Fuente:

scopus