Cadinane sesquiterpenes from the mushroom Lyophyllum transforme

Abstract:

Two rare cadinane-type sesquiterpenes, lyophyllone A (1) and lyophyllanetriol A (2), were isolated from the mushroom Lyophyllum transforme. The structures were elucidated on the basis of exhaustive NMR techniques, together with MS, UV-Vis and molecular modelling. The absolute configuration of lyophyllone A was determined by ab initio theoretical CD calculation performed by Density Functional Theory (DFT) using the B3PW91/6-31G(d,p) basis set. The experimental CD were found to be in good agreement with the corresponding population-weighted theoretical CD spectra, allowing for the determination of the absolute stereochemistry of the compound. © 2013 Elsevier B.V.

Año de publicación:

2013

Keywords:

• Absolute configuration
• Structure elucidation
• Cd
• Cadinane
• sesquiterpenes
• Lyophyllaceae
• TD-DFT calculations
• Lyophyllum transforme

Fuente:

scopus

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