Caracterización de moléculas bioactivas presente en los extractos de la anémona Condylactis gigantea

Abstract:

In recent decades, marine organisms have been targets of interest in the search for molecules with biological activity. Condylactis gigantean is an anemone present in the ocean floor soil; it contains venom-producing cells (nematocyst) used for hunting and self-defense. The aim of this study is to evaluate this organism’s extract in order to search for molecules with biological activity. From the total body extract, proteolytic activities were characterized by zigmogram in SDS-PAGE gels, as well as hemolytic activity and phospholipase A2. Proteolytic activity was found a in approximately 23KDa that is activated with temperature and is independent of pH and ions and two activities of metalloprotease nature with affinity to Na+, Ca2+ and Zn2+ of high molecular weigh; the hemolytic capacity and phospholipase A2 activity was determined; this leads us to the conclusion that the proteins present may be of interest as bioactive compounds.

Año de publicación:

2018

Keywords:

Fuente:

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