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Carbamazepine-induced porphyria cutanea tarda

Abstract:

A 32 years-old woman, with eight-years long depression disease, treated with clonazepam, carbamazepine and rebuxetine, referred a skin erosions in the dorsum of her hands and facial hypertrichosis. She also referred an increase in the intensity of her urine coloring. The complementary exam showed very high levels of porphyrines and coproporphyrines in 24-hour urine. When carbamazepine was withdrawn, clinical and metabolic recovery of her porphyria cutanea tarda become in few months. A carbamazepine-induced cutaneous porphyria diagnose was reported.