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A synaptogenic pacing cell line

Abstract:

The SK-N-BE(2c) is an I-type neuroblastoma that develops a strong pacing electrical response over time. This response is likely the result of a developing interconnected network, such that the regular pacemaker-like firing of individual cells becomes synchronous over time forming a Multi Unit Spikes signal (MUS). Immuno-fluorescence was used to show the presence of pre and postsynaptic markers, suggesting that MUS are the result of networking. Hence this cell line could prove as a useful model for synaptic dopaminergic pacing cell systems. © 2005 IEEE.

Año de publicación:

2005

Keywords:

    Fuente:

    scopusscopus

    Tipo de documento:

    Conference Object

    Estado:

    Acceso restringido

    Áreas de conocimiento:

      Áreas temáticas:

      • Enfermedades

      Contribuidores:

      Gaumond R.P.Gaumond R.P.
      Kowal J.Kowal J.
      Allcock H.R.Allcock H.R.
      Kim J.S.Kim J.S.
      Ricardo SilvaRicardo Silva
      Barrett E.W.Barrett E.W.