Chemical composition, enantiomeric distribution and AChE-BChE activities of the essential oil of Myrteola phylicoides (Benth) Landrum from Ecuador


Abstract:

The volatile constituents of the essential oil (EO) of Myrteola phylicoides (Benth) Landrum, from Ecuador, extracted by steam distillation have been analyzed. A total of 37 compounds, representing 90.30% the total essential oil sample were identified. Monoterpenes hydrocarbons (53.06%) and sesquiterpene hydrocarbons (35.24%) were the principal groups of compounds. The major components were identified as α-pinene (30.94%), (E)-caryophyllene (21.93%), β-pinene (14.45%) and α-humulene (9.56%). The essential oil of M. phylicoides showed weak in vitro activity against AChE inhibition with IC50 value 60.8 μg/mL and a low BChE activity with IC50 value >250 μg/mL. This is the first report on the chemical composition of the essential oil of this species.

Año de publicación:

2019

Keywords:

  • BChE
  • AChE
  • Myrteola phylicoides
  • Essential oil

Fuente:

googlegoogle
scopusscopus

Tipo de documento:

Article

Estado:

Acceso abierto

Áreas de conocimiento:

  • Bioquímica
  • Bioquímica
  • Bioquímica

Áreas temáticas:

  • Farmacología y terapéutica