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AB0511 SYSTEMIC LUPUS ERYTHEMATOSUS DISEASE ACTIVITY SCORE (SLE-DAS) VALIDATION IN ARGENTINIAN PATIENTS

Abstract:

Background Many activity indices have been developed for Systemic Lupus Erythematosus. However, they present important limitations due to the multi-organ compromise. The SLEDAI score and its different versions are widely used in daily practice and in clinical research. Diogo Jesus et al (2018) developed the SLE-DAS (Systemic Lupus Erythematosus Disease Activity Score), that include 17 items, 4 of them continuous. SLE-DAS assesses disease activity in the 28 previous days using an online calculator, with clinical characteristics non-evaluated by SLEDAI. It showed greater precision to measure disease activity, greater sensitivity to detect clinically significant changes and better performance to predict accumulated damage than SLEDAI. It has not yet been validated in Argentina. Objectives To determine the validity of the SLE-DAS score in a population of patients with SLE from Argentina. Methods A multicenter …