AB0524 Immunosuppressive Treatment in Patients with Primary SjÖgren Syndrome (PSS)

Abstract:

Background There is not enough evidence either to support the use of immunosuppressive drugs in pSS or for which specific clinical features they would be indicated. Objectives To evaluate the most frequently immunosuppressive drugs prescribed in pSS and to describe the clinical features that determined the indication,in a multicentric cohort of Argentinean patients with pSS. To analyze the clinical characteristics of patients with immunosuppressive therapy in comparison to patients that had not received it. Methods We analyzed subjects with pSS included in the data-base of the Argentine study group for SS (GESSAR). We considered the use of methotrexate, azathioprine, cyclophosphamide, leflunomide, mycophenolate, rituximab, belimumab and/or prednisone (>20mg/day). Results From 431 patients, 72 (16.7%) had received immunosuppressive therapy. Female: 92%; mean age: 59 years; mean time of the …

Año de publicación:

2015

Keywords:

Fuente:

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