AB0589 Involvement of Peripheral Nervous System in Primary SjÖgren Syndrome. a Gessar Analisys

Abstract:

Background Peripheral neuropathy (PN) is usually is a late onset event in primary Sjögren Syndrome (pSS) associated with purpura, cryoglobulinemia, hypocomplementemia and increased risk of lymphoma. Objectives To describe the frequency of PN in patients with pSS and identify related factors. Methods Adult patients in the GESSAR database who met 2002 criteria for pSS. Demographic, clinical, laboratory and electromyogram (EMG) findings were recorded. PN was defined with clinic manifestations and EMG. Other causes of PN were excluded. To compare groups, all patients with PN were included (cases) and a random sample of patients without PN (controls) with a 1:4 ratio was used. Mann-Whitney was used for numeric variables and χ2or Fisher9s for categorical. An α of 0.05 was considered significant. Results Of 368 patients, 95% were female. Mean age at analysis was 55 y/o (21-87) and 50 y/o (20-89 …

Año de publicación:

2015

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Fuente:

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