Clinopodium nubigenum (Kunth) Kuntze essential oil: Chemical composition, antioxidant activity, and antimicrobial test against respiratory pathogens

Abstract:

The essential oil of leaves and flowers of Clinopodium nubigenum (Kunth.) Kuntze (Lamiaceae) collected in the province of Pichincha-Ecuador was steam distilled and analyzed by gas chromatography mass spectrometry (GC/MS) to determine its chemical composition. The majority of the compounds identified were carvacrol acetate (42.1%), carvacrol (20.6%), pulegone (6.3%) and thymol (5.5%). Antioxidant activity was assessed by the assays of diphenylpicrylhydrazyl (DPPH)(IC50: 1.8 μl/ml), 2, 2′-azino-bis-3-ethylbenzthiazoline-6-sulphonic acid (ABTS)(IC50: 0.3 μl/ml) and β-carotene (IC50: 0.031 μl/ml) compared to Thymus vulgaris and butylated hydroxyanisole (BHA) as referents. The specie also shows a promising medicinal potential exhibiting significant antibacterial activity at different concentrations against Staphylococcus aureus (2.5% v/v), Streptococcus pyogenes (0.6% v/v), Streptococcus pneumoniae …

Año de publicación:

2018

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Fuente:

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