ACTG‐HIV symptoms changes in patients switched to RPV/FTC/TDF due to previous intolerance to CART. Interim analysis of the PRO‐STR study

Abstract:

Introduction Tolerability and convenience are crucial aspects for the long‐term success of combined antiretroviral therapy (cART). The aim of this study was to investigate the impact in routine clinical practice of switching to the single tablet regimen (STR) RPV/FTC/TDF in patients with intolerance to previous cART, in terms of patients’ well‐being, assessed by several validated measures. Methods Prospective, multicenter study. Adult HIV‐infected patients with viral load under 1.000 copies/mL while receiving a stable ART for at least the last three months and switched to RPV/FTC/TDF due to intolerance of previous regimen, were included. Analyses were performed by ITT. Presence/magnitude of symptoms (ACTG‐HIV Symptom Index), quality of life (EQ‐5D, EUROQoL & MOS‐HIV), adherence (SMAQ), preference of treatment and perceived ease of medication (ESTAR) through 48 weeks were performed …

Año de publicación:

2014

Keywords:

Fuente:

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