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Comparative Study of Chemical Composition and Biological Activity of Yellow, Green, Brown, and Red Brazilian Propolis

Abstract:

The chemical composition and biological activity of a sample of yellow propolis from Mato Grosso do Sul, Brazil (EEP-Y MS), were investigated for the first time and compared with green, brown, and red types of Brazilian propolis and with a sample of yellow propolis from Cuba. Overall, EEP-Y MS had different qualitative chemical profiles, as well as different cytotoxic and antimicrobial activities when compared to the other types of propolis assessed in this study and it is a different chemotype of Brazilian propolis. Absence of phenolic compounds and the presence of mixtures of aliphatic compounds in yellow propolis were determined by analysing 1H-NMR spectra and fifteen terpenes were identified by GC-MS. EEP-Y MS showed cytotoxic activity against human tumour strain OVCAR-8 but was not active against Gram-negative or Gram-positive bacteria. Our results confirm the difficulty of establishing a uniform quality standard for propolis from diverse geographical origins. The most appropriate pharmacological applications of yellow types of propolis must be further investigated.

Año de publicación:

2016

Keywords:

    Fuente:

    googlegoogle
    scopusscopus

    Tipo de documento:

    Article

    Estado:

    Acceso abierto

    Áreas de conocimiento:

    • Biotecnología
    • Bioquímica

    Áreas temáticas:

    • Microorganismos, hongos y algas
    • Bioquímica
    • Farmacología y terapéutica

    Contribuidores:

    Cardoso M.V.Cardoso M.V.
    Monteiro M.C.Monteiro M.C.
    De Oliveira F.D.C.E.De Oliveira F.D.C.E.
    Machado C.S.Machado C.S.
    Mokochinski J.B.Mokochinski J.B.
    Torres Y.R.Torres Y.R.
    De Campos M.S.De Campos M.S.
    Sawaya A.C.H.F.Sawaya A.C.H.F.
    Ferreira A.G.Ferreira A.G.
    Osmany Cuesta-RubioOsmany Cuesta-Rubio
    Ferreira R.G.Ferreira R.G.
    Lira T.O.D.Lira T.O.D.
    Pessoa C.Pessoa C.