Regresar

Comparative efficacies of TAK-187, a long-lasting ergosterol biosynthesis inhibitor, and benznidazole in preventing cardiac damage in a murine model of Chagas' disease

Abstract:

We carried out a comparative study of benznidazole and TAK-187, a long-lasting ergosterol biosynthesis inhibitor, with a murine model of Chagas' disease. The results indicated that TAK-187 was more effective than benznidazole in preventing Trypanosoma cruzi-induced cardiac damage in experimental animals. Copyright © 2005, American Society for Microbiology. All Rights Reserved.

Año de publicación:

2005

Keywords:

    Fuente:

    scopusscopus

    Tipo de documento:

    Article

    Estado:

    Acceso restringido

    Áreas de conocimiento:

    • Infección
    • Farmacología

    Áreas temáticas:

    • Farmacología y terapéutica
    • Microorganismos, hongos y algas
    • Enfermedades

    Contribuidores:

    Basombŕo M.A.Basombŕo M.A.
    Corrales M.Corrales M.
    Urbina J.A.Urbina J.A.
    Rubén Marino CardozoRubén Marino Cardozo
    Segura M.A.Segura M.A.