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Comparative genomic and functional analysis of Arthrobacter sp. UMCV2 reveals the presence of luxR-related genes inducible by the biocompound N, N-dimethylhexadecilamine

Abstract:

Quorum sensing (QS) is a bacterial cell-cell communication system based on the production, release, and detection of signal molecules called autoinducers (AI). QS regulates gene expression in response to changes in bacterial population density and produces coordinated behavior, based on environmental conditions (Fuqua et al., 1994; Waters and Bassler, 2005; Papenfort and Bassler, 2016). Cellular functions regulated by QS include bioluminescence, antibiotic synthesis, virulence factor production, biofilm induction, sporulation, and swarming motility (Polkade et al., 2016; Bramhachari et al., 2018). The lux operon, responsible for bioluminescence in the model organism Vibrio fischeri (Aliivibrio fischeri), is composed of six structural genes (luxA-E and luxG) and the regulatory genes luxI and luxR that encode homonym proteins (Fuqua et al., 1996; Miller and Bassler, 2001). LuxI is an acyl-synthase of …