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Copper, zinc, calcium and magnesium profiles in subjects with autistic disorder according to their functioning level

Abstract:

Either an excess or a deficiency of minerals have been involved in the etiology of autistic disorder. The objective of this study was to determine serum concentration and dietary intake of these elements in 30 subjects with autistic disorder classified according to their functioning level and 20 control subjects. We detected statistically significant differences (p < 0.05) related to high levels of Cu and low levels of Mg in subjects with autistic disorder compared to control group. Cooper serum level in subjects with high-functioning autism was higher than the control group and subgroups of subjects with this disorder. Concluding, results point to a possible imbalance in cooper homeostasis in this disorder as well as a physiological regulation of cooper in subjects with high-functioning autism, which could be influencing the expression of low symptoms in this subgroup of subject. ©2012 Dustri-Verlag Dr. K. Feistle.