Correlation analysis of surnames and Y-chromosome genetic heritage in 3 provinces of southwestern Colombia

Abstract:

GOMEZ, Alberto; AVILA, Sandra J and BRICENO, Ignacio. De genotipos e isonimias: análisis de correlación entre el apellido y el patrimonio genético heredado en el cromosoma Y en la población de tres departamentos del suroccidente colombiano. Biomédica [online]. 2008, vol. 28, n. 3, pp. 357-370. ISSN 0120-4157. Introduction. In Colombia, surnames are characters usually passed to the children by the father, and they have been compared to neutral alleles associated with the Y-chromosome. Objective. Population frequencies were determined for 17 short tandem repeats (STR) DNA markers on the Y-chromosome to compare the two identity codes and define the correlation between haplotypes and surnames in each individual. Materials and methods. DNA was extracted from blood samples from 308 male individuals in provinces of Valle del Cauca, Cauca and Nariño, all in southwestern Colombia. Sample DNA was analyzed with the commercial kit AmpFLSTR® Yfiler (Applied Biosystems) and examined for the following 17 Y-chromosome STR markers: DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a/b, DYS437, DYS438, DYS439, DYS448, DYS456, DYS458, DYS635 and Y-GATA-H4. The frequencies of molecular haplotypes were associated with the surname reported by each individual, and a correlation table was constructed. Amerindian and European surnames were associated with the presence of allele DYS19/13, a characteristic of Amerindian populations. Results. Allele frequencies were reported for each of the 17 STR markers in the southwestern region of Colombia-high genetic and haplotypic …

Año de publicación:

2008

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