Corrigendum: “Nuclear proteasomal degradation of Saccharomyces cerevisiae inorganic pyrophosphatase Ipp1p, a nucleocytoplasmic protein whose stability depends on its subcellular localization” [Biochim. Biophys. Acta Mol. Cell Res. 1866 (2019) 1019–1033, (S0167488918303938), (10.1016/j.bbamcr.2019.02.015)]


Abstract:

This corrigendum clarifies the presentation of some experimental data in the anti-GFP Western blot image showed in the lower panel picture of Fig. 3B of this article, which appears to have a differential splice. There is a concern with the anti-GFP Western blot image of Fig. 3B (four lanes from the left). After contacting the coauthor who performed the experiment, it was verified that the original Western blot image was altered by placing the first two lanes (control, native IPP1-GFP chimera) to the left of the second pair of lanes (mutant Ipp1-1-GFP chimera), although in the original image they were to their right (see the uncropped original image of the anti-GFP Western blot). This was done so that these image data would match the order of the control Western blots below (anti-HK1 and anti-H3) and the specific activity data above, in published Fig. 3B.[Formula presented] Therefore, a corrected version of Fig. 3 is given here showing a vertical separation bar between the second and third lanes of the anti-GFP Western blot in Fig. 3B panel, to indicate that there is a physical discontinuity between these lanes (see Fig. 3 Corrected version). The same Fig. 3 legend of the published article is applicable to the corrected figure shown here.[Formula presented] We are confident that these data are valid, and that this image modification does not alter the biological significance of the presented results. We are also confident in the validity of the overall conclusions of the article, which has so far been positively cited in the scientific literature. We do recognize, however, the inappropriate action taken with the anti-GFP Western blot image in Fig. 3B and apologize for this.

Año de publicación:

2023

Keywords:

    Fuente:

    scopusscopus

    Tipo de documento:

    Other

    Estado:

    Acceso abierto

    Áreas de conocimiento:

    • Biología molecular
    • Bioquímica

    Áreas temáticas:

    • Bioquímica
    • Historia natural de los organismos