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In vitro and in vivo protective effect of orphenadrine on glutamate neurotoxicity
ArticleAbstract: The anticholinergic drug orphenadrine is used in the treatment of Parkinson's disease. In this studyPalabras claves:Excitotoxicity, Heat shock proteins, Neurodegeneration, Orphenadrine, Peripheral-type benzodiazepine-receptor, RATAutores:Adan J., Antoni Camins, Camarasa J., Escubedo E., Gabriel C., Maria Martínez J., Pallás M., Sureda F.X.Fuentes:scopusTackling lipophilicity of peptide drugs: Replacement of the backbone n -methyl group of Cilengitide by N -oligoethylene glycol (N -OEG) chains
ArticleAbstract: Cilengitide is an RGD-peptide of sequence cyclo[RGDfNMeV] that was was developed as a highly activePalabras claves:Autores:Adan J., Alberício F., Fernandez-Llamazares A.I., Jan Spengler, Mitjans F.Fuentes:googlescopusThe backbone N-(4-azidobutyl) linker for the preparation of peptide chimera
ArticleAbstract: A robust synthetic strategy for the introduction of the N-(4-azidobutyl) linker into peptides usingPalabras claves:Autores:Adan J., Alberício F., Fernandez-Llamazares A.I., García J., Jan Spengler, Meunier D., Mitjans F.Fuentes:googlescopus