Mostrando 2 resultados de: 2
Astemizole Synergizes Calcitriol Antiproliferative Activity by Inhibiting CYP24A1 and Upregulating VDR: A Novel Approach for Breast Cancer Therapy
ArticleAbstract: Background: Calcitriol antiproliferative effects include inhibition of the oncogenic ether-à-go-go-1Palabras claves:Autores:Avila-Chávez E., David B., Díaz L., Gamboa-Dominguez A., García-Becerra R., García-Quiroz J., Halhali A., Javier Camacho, Larrea F., Medina-Franco H., Ordaz-Rosado D., Rivas-Suárez M., Rodríguez P., Santos-Martínez N.Fuentes:scopusIn vivo dual targeting of the oncogenic ether-à-go-go-1 potassium channel by calcitriol and astemizole results in enhanced antineoplastic effects in breast tumors
ArticleAbstract: Background: The oncogenic ether-à-go-go-1 potassium channel (EAG1) activity and expression are necesPalabras claves:Breast Cancer, Eag1, Ki-67, Targeted therapy, vitamin D, Vitamin D receptorAutores:Avila-Chávez E., David B., Díaz L., Esparza-López J., Gamboa-Dominguez A., García-Becerra R., García-Quiroz J., Halhali A., Ibarra-Sánchez M., Javier Camacho, Larrea F., Ordaz-Rosado D., Santos-Martínez N., Villanueva O.Fuentes:scopus