Mostrando 7 resultados de: 7
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Neuroscience(2)
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scopus(7)
Carbonyl stress and NMDA receptor activation contribute to methylglyoxal neurotoxicity
ArticleAbstract: Methylglyoxal (MG) is a reactive α-ketoaldehyde physiologically generated as a by-product of glycolyPalabras claves:Carbonyl stress, Free radicals, methylglyoxal, Mitochondria, Neurodegeneration, NMDA receptorsAutores:Allgaier C., Antoni Camins, Garcia De Arriba S., García-Jordà E., Krügel U., Lewerenz A., Münch G., Nieber K., Pallás M., Regenthal R., Verdaguer E., Vissiennon Z.Fuentes:scopusEvaluation of the neuronal apoptotic pathways involved in cytoskeletal disruption-induced apoptosis
ArticleAbstract: The cytoskeleton is critical to neuronal functioning and survival. Cytoskeletal alterations are invoPalabras claves:calcium, Calpainsl, Caspases, Cytoskeleton, Serine-proteasesAutores:Allgaier C., Antoni Camins, Arriba S.G.D., Jiménez A., Jordá E.G., Pallás M., Verdaguer E.Fuentes:scopusDifferent capacities of various NMDA receptor antagonists to prevent ischemia-induced neurodegeneration in human cultured NT2 neurons
ArticleAbstract: In the present study, human NT2 neurons obtained from embryonic teratocarcinoma (NT2) cells were estPalabras claves:Cultured human NT2 neurons, Glycine binding site antagonists B, immunocytochemistry, ischemia, NMDA receptors, Patch-clamp recordingsAutores:Allgaier C., Antoni Camins, Garcia De Arriba S., Grüner K., Pallás M., Verdaguer E., Wagner A., Wegner F., Wohlfahrt K.Fuentes:scopusNeuroprotection associated with alternative splicing of NMDA receptors in rat cortical neurons
ArticleAbstract: 1 Exposure of cultured cortical neurons to elevated extracellular K + concentrations (25 mM) inducesPalabras claves:Calpain, Caspase-3, Cultured cortical neurons, neuroprotection, NMDA receptors, Receptor adaptationAutores:Allgaier C., Antoni Camins, de Arriba S.G., Jaekel B., Mühlberg K., Nörenberg W., Pallás M., Reichenbach A., Verdaguer E.Fuentes:scopusImplication of cyclin-dependent kinase 5 in the neuroprotective properties of lithium
ArticleAbstract: Although numerous studies have demonstrated a neuroprotective and anti-apoptotic role of lithium inPalabras claves:apoptosis, Cdk5/p25, Cerebellar granule neurons, GSK-3β, LithiumAutores:Allgaier C., Antoni Camins, Canudas A.M., Garcia De Arriba S., Jiménez A., Jordá E.G., Pallás M., Verdaguer E.Fuentes:scopusInhibition of cyclin-dependent kinases is neuroprotective in 1-methyl-4-phenylpyridinium-induced apoptosis in neurons
ArticleAbstract: The biochemical pathways involved in neuronal cell death in Parkinson's disease are not completely cPalabras claves:apoptosis, Cerebellar granule cells, Cyclin dependent kinases, flavopiridol, Vitamin EAutores:Allgaier C., Alvira D., Antoni Camins, de Arriba S.G., Jiménez A., Matute C., Pallás M., Tajes M., Trullàs R., Verdaguer E.Fuentes:scopusInhibitors of cyclin-dependent kinases: Potential drugs for the treatment of neurodegenerative disorders?
ReviewAbstract: The pharmacological treatment of neurodegenerative disorders such as Alzheimer's disease, Parkinson'Palabras claves:Autores:Allgaier C., Alvira D., Antoni Camins, Canudas A.M., Garcia De Arriba S., Pallás M., Sureda F.X., Verdaguer E.Fuentes:scopus