Mostrando 5 resultados de: 5
Filtros aplicados
Publisher
Archives of Biochemistry and Biophysics(2)
Biochemistry(1)
Endocrine Research(1)
Journal of Clinical Endocrinology and Metabolism(1)
Área temáticas
Farmacología y terapéutica(4)
Bioquímica(3)
Enfermedades(2)
Fisiología humana(1)
Ginecología, obstetricia, pediatría, geriatría(1)
Origen
scopus(5)
5α-reduced C<inf>21</inf> steroids are substrates for human cytochrome P450c17
ArticleAbstract: The 5α-reduction of testosterone in target tissues is a key step in androgen physiology; however, 5αPalabras claves:17-hydroxylase/17,20-lyase, 3α-Hydroxysteroid dehydrogenase, 5α-reductase, Allopregnanolone, Androstanediol, CYP17, Cytochrome b 5, Dihydrotestosterone, P450c17, Sexual differentiationAutores:Gupta M.K., Guryev O.L., Richard J. AuchusFuentes:scopusPitfalls in characterizing P450c17 mutations associated with isolated 17,20-lyase deficiency
ArticleAbstract: The cytochrome P450c17 enzyme system performs both the 17α-hydroxylase and 17,20-lyase reactions inPalabras claves:Autores:Geller D.H., Gupta M.K., Richard J. AuchusFuentes:scopusTowards a unifying mechanism for CYP17 mutations that cause isolated 17, 20-lyase deficiency
Conference ObjectAbstract: Cytochrome P450c17 (CYP17) is a single hemoprotein that catalyzes both the 17x-hydroxylase and 17, 2Palabras claves:Autores:Gupta M.K., Richard J. AuchusFuentes:scopusWhy human cytochrome P450c21 is a progesterone 21-hydroxylase
ArticleAbstract: Human cytochrome P450c21 (steroid 21-hydroxylase, CYP21A2) catalyzes the 21-hydroxylation of progestPalabras claves:Autores:Dwyer C., Gupta M.K., Mizrachi D., Richard J. Auchus, Sharma K.K., Wang Z., Xu K.Fuentes:scopusThe enantiomer of progesterone (ent-progesterone) is a competitive inhibitor of human cytochromes P450c17 and P450c21
ArticleAbstract: Human cytochrome P450c17 (17α-hydroxylase, 17,20-lyase) (CYP17) and cytochrome P450c21 (21-hydroxylaPalabras claves:17α-Hydroxylase/17,20-lyase, 21-hydroxylase, CYP17, CYP21, Cytochrome P450c17, Cytochrome P450c21, ent-Progesterone, Enzyme inhibition, molecular dynamics, Type I difference spectrumAutores:Boswell C., Bruce K., Covey D.F., Gupta M.K., Kumar A., Rath N., Richard J. AuchusFuentes:scopus