5α-reduced C<inf>21</inf> steroids are substrates for human cytochrome P450c17

Article

Abstract: The 5α-reduction of testosterone in target tissues is a key step in androgen physiology; however, 5α

Palabras claves:

17-hydroxylase/17,20-lyase, 3α-Hydroxysteroid dehydrogenase, 5α-reductase, Allopregnanolone, Androstanediol, CYP17, Cytochrome b 5, Dihydrotestosterone, P450c17, Sexual differentiation

Autores:

Gupta M.K., Guryev O.L., Richard J. Auchus

Fuentes:

scopus