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Generation of a highly sensitive reporter plasmid for the detection of the transcripcional response to hypoxia
ArticleAbstract: Decreased oxygen supply to the tissues at both systemic and local level induces a genic program whicPalabras claves:HIF-1α, Hypoxia, transcription factorsAutores:Alfranca A., Aragonés J., Manuel Ortiz de Landázuri, Temes E., Vara A.Fuentes:scopusThe von Hippel Lindau/hypoxia-inducible factor (HIF) pathway regulates the transcription of the HIF-proline hydroxylase genes in response to low oxygen
ArticleAbstract: Most of the genes induced by hypoxia are regulated by a family of transcription factors termed hypoxPalabras claves:Autores:Castellanos M.C., Cuevas Y., Manuel Ortiz de Landázuri, Martin-Puig S., Olmos G., Peso L.D., Temes E.Fuentes:scopus