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CYP450 Genotype/Phenotype Concordance in Mexican Amerindian Indigenous Populations-Where to from Here for Global Precision Medicine?
ArticleAbstract: Global precision medicine demands characterization of drug metabolism and phenotype variation in divPalabras claves:Biomarkers, developing world omics, drug metabolism variation, global personalized medicine, Systems DiagnosticsAutores:Adrián LLerena, de Andrés F., Naranjo M.E.G., Ramos B., Sosa-Macías M.G.Fuentes:scopusLessons from Cuba for global precision medicine: CYP2D6 genotype is not a robust predictor of CYP2D6 ultrarapid metabolism
ArticleAbstract: A long-standing question and dilemma in precision medicine is whether and to what extent genotypingPalabras claves:Biomarkers, developing world omics, Diagnostic Medicine, Innovation Systems, personalized medicine, system diagnosticsAutores:Adrián LLerena, Calzadilla L.R., de Andrés F., Dorado P., González I., Naranjo M.E.G., Penãs-Lledó E.M.Fuentes:scopusTo Genotype or Phenotype for Personalized Medicine? CYP450 Drug Metabolizing Enzyme Genotype-Phenotype Concordance and Discordance in the Ecuadorian Population
ArticleAbstract: Genetic variations within the cytochrome P450 (CYP450) superfamily of drug metabolizing enzymes confPalabras claves:Biomarkers, developing world omics, Diagnostic Medicine, Innovation Systems, personalized medicine, Systems DiagnosticsAutores:Adrián LLerena, de Andrés F., Enrique Terán, Francisco J.López Hernández, Santiago TeránFuentes:googlescopusWater pipe (Shisha, Hookah, Arghile) Smoking and Secondhand Tobacco Smoke Effects on CYP1A2 and CYP2A6 Phenotypes as Measured by Caffeine Urine Test
ArticleAbstract: Public policies to stop or reduce cigarette smoking and exposure to secondhand smoke and associatedPalabras claves:Biomarkers, developing world omics, Diagnostic Medicine, drug development and OMICS, personalized medicineAutores:Adrián LLerena, de Andrés F., Erciyas K., Gündoǧar H., Güngör K., Karakaş Ü., Kimyon S., Mete A., Özdemir V., Yllmaz S.G.Fuentes:scopus