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scopus(8)
An overview of investigational antiapoptotic drugs with potential application for the treatment of neurodegenerative disorders
ReviewAbstract: Importance of the field: The increase in life expectancy in developed countries has given rise to sePalabras claves:Alzheimer's disease, apoptosis, Neuroprotective drugs, Parkinson's DiseaseAutores:Antoni Camins, Folch J., Junyent F., Pallás M., Sureda F.X., Verdaguer E., Zárate C.B.Fuentes:scopusInhibition of ataxia telangiectasia-p53-E2F-1 pathway in neurons as a target for the prevention of neuronal apoptosis
ReviewAbstract: Over the last few decades, understanding of the mechanisms involved in the process of neuronal'cellPalabras claves:apoptosis, Cyclin dependent kinases, E2F-1, NeuronAutores:Antoni Camins, Canudas A.M., Folch J., Pallás M., Verdaguer E., Zárate C.B.Fuentes:scopusPeripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer’s Disease
ArticleAbstract: There is growing evidence that obesity associated with type 2 diabetes mellitus (T2DM) and aging arePalabras claves:Alzheimer’s disease, APPswe/PS1dE9, DIABÉTES, high-fat diet, Memantine, obesityAutores:Antoni Camins, Auladell C., Busquets O., Cabrera H., Carro E., Casadesús G., Ettcheto M., Folch J., García M.L., Gómez-Mínguez Y., Sanchez-Lopez E., Vázquez-Carrera M., Zárate C.B.Fuentes:scopusLong-term exposition to a high fat diet favors the appearance of β-amyloid depositions in the brain of C57BL/6J mice. A potential model of sporadic Alzheimer's disease
ArticleAbstract: Aims The sporadic and late-onset form of Alzheimer's disease (AD) constitutes the most common form oPalabras claves:AD, Alzheimer's disease, AMP-activated protein kinase, AMPK, ANS, autonomic nervous system, Aβ, BACE1, BBB, beta-site APP-cleaving enzyme 1, brain blood barrier, Cerebrospinal fluid, CSF, diet-induced obesity, DIO, HCD, HFD, high calorie diet, high-fat diet, IGF-1, Insulin-like growth factor-1, late-onset Alzheimer's disease, LOAD, MAPK, mitogen-activated protein kinase, protein tyrosine phosphatase 1β, PTP1β, T2DM, Type 2 Diabetes mellitus, β-AmyloidAutores:Antoni Camins, Auladell C., Busquets O., Ettcheto M., Folch J., Pallás M., Verdaguer E., Zárate C.B.Fuentes:scopusJNK Isoforms Are Involved in the Control of Adult Hippocampal Neurogenesis in Mice, Both in Physiological Conditions and in an Experimental Model of Temporal Lobe Epilepsy
ArticleAbstract: Neurogenesis in the adult dentate gyrus (DG) of the hippocampus allows the continuous generation ofPalabras claves:adult hippocampal neurogenesis, JNK isoforms, Kainic acid, Knockout miceAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Folch J., Landa J., Olloquequi J., Rabaza M., Verdaguer E., Zárate C.B.Fuentes:scopusJNK1 inhibition by Licochalcone A leads to neuronal protection against excitotoxic insults derived of kainic acid
ArticleAbstract: The mitogen-activated protein kinase family (MAPK) is an important group of enzymes involved in cellPalabras claves:Epilepsy, hippocampus, Kainic acid, Licochalcone A, NeurodegenerationAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Folch J., Verdaguer E., Zárate C.B.Fuentes:scopusKB-R7943 reduces 4-aminopyridine-induced epileptiform activity in adult rats after neuronal damage induced by neonatal monosodium glutamate treatment
ArticleAbstract: Background: Neonatal monosodium glutamate (MSG) treatment triggers excitotoxicity and induces a degePalabras claves:Entorhinal cortex, hippocampus, KB-R7943, Monosodium glutamate, NCX1-3, seizuresAutores:Antoni Camins, Cardenas-Castillo J.A., Gutierrez-Barajas P.E., Hernandez-Ojeda M., Ureña-Guerrero M.E., Zárate C.B.Fuentes:scopusThe Involvement of Peripheral and Brain Insulin Resistance in Late Onset Alzheimer’s Dementia
ReviewAbstract: Nowadays, Alzheimer’s disease (AD) is a severe sociological and clinical problem. Since it was firstPalabras claves:Alzheimer’s disease, Insulin Resistance, Mediterranean diet, neuroinflammation and neurodegeneration, obesity, Type 2 Diabetes mellitusAutores:Antoni Camins, Auladell C., Bulló M., Busquets O., Cano A., Casadesús G., Espinosa-Jimenez T., Ettcheto M., Folch J., García M.L., Olloquequi J., Sanchez-Lopez E., Zárate C.B.Fuentes:scopus