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Apoptosis(1)
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scopus(5)
Antiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases
ReviewAbstract: The purpose of this review is to discuss potential pathways involved in the pathogenesis of neurodegPalabras claves:Alzheimer's disease, apoptosis, Cyclin-dependent kinases, Glutamate receptors, Neuronal cell death, Neuroprotective drugs. apoptosis, Parkinson's DiseaseAutores:Antoni Camins, Auladell C., Canudas A.M., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Sureda F.X., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusAntiapoptotic effects of roscovitine on camptothecin-induced DNA damage in neuroblastoma cells
ArticleAbstract: In the present study dopaminergic neuroblastoma B65 cells were exposed to Camptothecin (CPT) (0.5-10Palabras claves:Ataxia telangiectasia mutated, camptothecin, cell cycle, RoscovitineAutores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Pizarro J.G., Verdaguer E., Zárate C.B.Fuentes:scopusGene expression profile in JNK3 null mice: A novel specific activation of the PI3K/AKT pathway
ArticleAbstract: JNK3 is mainly expressed in the CNS and it plays a crucial role in neuronal death in several neurodePalabras claves:Akt, Gene profiling, JNK, Neurodegeneration, neuroprotection, PI3KAutores:Antoni Camins, Auladell C., De Lemos M.L., Ferrer I., Folch J., Junyent F., Ortuo-Sahagún D., Pallás M., Romero R., Verdaguer E., Zárate C.B.Fuentes:scopusHIF-1α expression in the hippocampus and peripheral macrophages after glutamate-induced excitotoxicity
ArticleAbstract: Hypoxia-inducible factor-1 alpha (HIF-1α) is a master transcription factor that regulates the responPalabras claves:EPO, Excitotoxicity, HIF-1 alpha, hippocampus, Macrophages, VEGFAutores:Antoni Camins, Armendáriz-Borunda J., Chaparro-Huerta V., Flores-Soto M.E., Gudiño-Cabrera G., Pallás M., Rivera-Cervantes M.C., Torres-Mendoza B.M., Vázquez-Valls E., Zárate C.B.Fuentes:scopusStudy of the pathways involved in apoptosis induced by PI3K inhibition in cerebellar granule neurons
ArticleAbstract: In the present study we focused in the PI3K/Akt pathway which plays a key role in neuronal survival.Palabras claves:BrdU, Caspase-6, Cdk5/p25, cell cycle, LY294002Autores:Antoni Camins, Auladell C., Folch J., Junyent F., Palls M., Pelegrí Gabalda C., Torre A.V.D.L., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopus