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Allelic loss at 1p and 19q frequently occurs in association and may represent early oncogenic events in oligodendroglial tumors
ArticleAbstract: The molecular mechanisms underlying the genesis and progression of oligodendroglial tumors are poorlPalabras claves:Autores:de Campos J.M., Elena Kusak M., Josefa Bello M., Paola E. Leone, Pestana A., Rey J.A., Sarasa J.L., Vaquero J.Fuentes:googlescopusAllelic status of chromosome 1 in neoplasms of the nervous system
ArticleAbstract: By using five highly polymorphic markers, the allelic status of chromosome 1 was established in a sePalabras claves:Autores:Bello M.J., Cusak M.E., de Campos J.M., García-Miguel P., Hernández-Moneo J.L., Nebreda P., Paola E. Leone, Pestana A., Queizan A., Rey J.A., Sarasa J.L., Vaquero J.Fuentes:googlescopusImplications of a RAD54L polymorphism (2290C/T) in human meningiomas as a risk factor and/or a genetic marker
ArticleAbstract: Background: RAD54L (OMIM 603615, Locus Link 8438) has been proposed as a candidate oncosupressor inPalabras claves:Autores:Alonso J., Cesar Paz-y-Miño, Mendiola M., Paola E. Leone, Pestana A.Fuentes:googlescopusSearch for mutations of the hRAD54 gene in sporadic meningiomas with deletion at 1p32
ArticleAbstract: The hRAD54 gene is related to a family of genes involved in DNA recombination and repair and encodesPalabras claves:1p deletion mapping, Allelic losses, hRAD54, Meningiomas, Tumor progressionAutores:Alonso J., Bello M.J., de Campos J.M., Kusak M.E., Mendiola M., Paola E. Leone, Pestana A., Rey J.A., Sarasa J.L., Vaquero J.Fuentes:googlescopusSix novel mutations in the NF2 tumor suppressor gene
ArticleAbstract: Six novel mutations were identified in the NF2 tumor suppressor gene in a panel of meningiomas and nPalabras claves:LOH 22q, MENINGIOMA, Mutations, NF2 gene, SchwannomaAutores:Bello M.J., de Campos J.M., Kusak M.E., Mendiola M., Paola E. Leone, Pestana A., Rey J.A., Sarasa J.L., Vaquero J.Fuentes:googlescopusNF2 gene mutations and allelic status of 1p, 14q and 22q in sporadic meningiomas
ArticleAbstract: Formation of meningiomas and their progression to malignancy may be a multi-step process, implying aPalabras claves:1p and 14q deletion mapping, Allelic losses, Meningiomas, NF2, Tumor progressionAutores:Bello M.J., de Campos J.M., Paola E. Leone, Pestana A., Rey J.A., Sarasa J.L., Vaquero J.Fuentes:googlescopusMolecular abnormalities of chromosome 19 in malignant gliomas: Preferential involvement of the 19q13.2-q13.4 region
ArticleAbstract: A deletion mapping analysis of chromosome 19 was performed on a series of 101 samples derived from mPalabras claves:astrocytoma, chromosome 19, glioblastoma multiforme, gliomasAutores:Bello M.J., de Campos J.M., Kusak M.E., Nebreda P., Paola E. Leone, Pestana A., Rey J.A., Sarasa J.L., Vaquero J.Fuentes:scopusTwo new mutations and three novel polymorphisms in the RB1 gene in Ecuadorian patients
ArticleAbstract: RB1 is the gene responsible for retinoblastoma, the most common malignant intraocular tumor of infanPalabras claves:Cancer susceptibility, ECUADOR, mutation, polymorphism, RB1, RetinoblastomaAutores:Alonso J., Cesar Paz-y-Miño, Jervis P., Paola E. Leone, Pestana A., Vega M.E.Fuentes:googlescopus