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2,5-Diketopiperidine derivatives as non-peptide ligands for cholecystokinin receptors
ArticleAbstract: Easily accessible 2,5-diketopiperidines have been used as templates for the construction of Trp-PhePalabras claves:Autores:Del Río J., Dominguez M.J., Fortuno A., Garcı́a-López M.T., Gonzalez-Muniz R., Herranz R., Santiago J. BallazFuentes:googlescopus2-Oxopyrrolidines and 6-oxoperhydropyrrolo[1,2-a]pyrazines as templates in the search for nonpeptide cholecystokinin ligands
ArticleAbstract: In order to find new classes of non-peptide cholecystokinin (CCK) ligands, the conformational restriPalabras claves:2-Oxopyrrolidine, Cholecystokinin mimetic, Perhydropyrrolo[1,2-a]pyrazineAutores:Cenarruzabeitia E., Del Río J., Garcı́a-López M.T., Gonzalez-Muniz R., Herranz R., LaTorre M., Martín-Martínez M., Santiago J. BallazFuentes:googlescopusCCK-4 restricted analogues containing a 3-oxoindolizidine skeleton
ArticleAbstract: A series of CCK-4 restricted analogues, incorporating a 3-oxoindolizidine bicyclic lactam as conformPalabras claves:Autores:Barber A., Del Río J., Dominguez M.J., Garcı́a-López M.T., Gonzalez-Muniz R., Herranz R., Martín-Martínez M., Santiago J. BallazFuentes:googlescopusCCK-mediated response in the activation of 5-HT receptor types in the guinea-pig ileum
ArticleAbstract: The possible interaction between cholecystokinin (CCK) and 5- hydroxytryptamine (5-HT) was evaluatedPalabras claves:Cholecystokinin, Contractile responses, Guinea-pig, Ileum, INTERACTION, SerotoninAutores:Barber A., Del Río J., Fortuno A., Santiago J. BallazFuentes:googlescopusFacilitation by 8-OH-DPAT of passive avoidance performance in rats after inactivation of 5-HT(1A) receptors
ArticleAbstract: 1. Pretraining administration of 8-hydroxy-2-di-n-propylamino-tetralin (8-OH-DPAT 0.1 mg kg-1), a 5-Palabras claves:5-HT(1A) receptors, 8-OH-DPAT, EEDQ, hippocampus, Passive avoidanceAutores:Del Río J., Frechilla D., García-Osta A., Otano A., Santiago J. BallazFuentes:googlescopusMDMA ('Ecstasy') enhances 5-HT(1A) receptor density and 8-OH-DPAT- induced hypothermia: Blockade by drugs preventing 5-hydroxytryptamine depletion
ArticleAbstract: One week after a single administration of 3,4- methylenedioxymethamphetamine (MDMA · HCl, 30 mg/kg iPalabras claves:5-HT (serotonin, 5- hydroxytryptamine), 5-HT(1A) receptor, 8-OH-DPAT (8-hydroxy-2-(di-n- propylamino)tetralin), MDMA (3,4-methylenedioxymethamphetamine), TEMPERATUREAutores:Aguirre N., Del Río J., Lasheras B., Santiago J. BallazFuentes:googlescopusSynthesis and molecular modeling of new 1-aryl-3-[4-arylpiperazin-1-yl]-1-propane derivatives with high affinity at the serotonin transporter and at 5-HT<inf>1A</inf> receptors
ArticleAbstract: It has been proposed that 5-HT1A receptor antagonists augment the antidepressant efficacy of selectiPalabras claves:Autores:Del Castillo J., Del Río J., Donzella G., Guccione S., Hervías I., Krovat E., Langer T., Lasheras B., Martínez-Esparza J., Monge A., Mourelle M., Oficialdegui A., Orús L., Pérez-Silanes S., Poptodorov K., Santiago J. Ballaz, Tordera R.Fuentes:googlescopusSynthesis and stereochemical structure activity relationships of 1,3- dioxoperhydropyrido[1,2-c]pyrimidine derivatives: Potent and selective cholecystokinin-a receptor antagonists
ArticleAbstract: The synthesis and stereochemical structure-activity relationships of a new class of potent and selecPalabras claves:Autores:Barber A., Bartolomé-Nebreda J.M., Del Río J., Fortuno A., Garcı́a-López M.T., Gómez-Monterrey I., Gonzalez-Muniz R., Herranz R., Martín-Martínez M., Santiago J. BallazFuentes:googlescopus