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Composition and cytotoxic activity of essential oils from Croton matourensis and Croton micans from Venezuela
ArticleAbstract: The chemical composition and cytotoxic activity of the essential oils extracted from leaves of CrotoPalabras claves:Croton matourensis, Croton micans, Cytotoxicity, Essential oil, Fenchyl acetate, MethyleugenolAutores:Alírica Isabel Suárez, Arvelo F.A., Chavez K., Compagnone R.S., Mateu E., Orsini G.Fuentes:scopus11-deoxyfistularin-3, a new cytotoxic metabolite from the caribbean sponge Aplysina fistularis insularis
ArticleAbstract: 11-Deoxyfistularin-3 (1), a new bromotyrosine derivative, was isolated among other known compounds sPalabras claves:Autores:Abrams O., Alírica Isabel Suárez, Arvelo F.A., Avila R., Compagnone R.S., Merentes E., Piña I.C., Rangel H.R.Fuentes:scopusA new indole-alkaloid and a new phenolic-glycoside with cytotoxic activity from Strychnos fendleri
ArticleAbstract: A new indole alkaloid strychnosinol (1) and a new phenolic-glycoside (2) were isolated from the barkPalabras claves:Cytotoxicity, phenolic glycoside, Strychnos fendleri, strychnosinolAutores:Alírica Isabel Suárez, Arvelo F.A., Mancebo M., Monache F.D., Sojo F.J., Tillett S., Tirri M.M.Fuentes:scopusCytotoxic and proapoptotic activity of ent-16β-17α- dihydroxykaurane on human mammary carcinoma cell line MCF-7
ArticleAbstract: Here we describe the cytotoxic and proapoptotic effect of an ent-kaurane (ent-16β-17α-dihydroxykauraPalabras claves:Anticancer agents, apoptosis, BCL2, Cytotoxic activity, Ent-kaurane, Telomerase activityAutores:Alírica Isabel Suárez, Arvelo F.A., Compagnone R.S., Galindo-Castro I., Luis Ramírez J., Mendoza R., Morales A., Pérez P.Fuentes:scopusCytotoxic effects of the monomer and dimer of 3, 4-seco-ent-kaurene from Croton micans and their interaction with antitumoral drugs on cellular line of human prostate cancer
ArticleAbstract: The cytotoxic activity of two bioactive molecules obtained from Croton species, caracasine acid (monPalabras claves:Combination index, Croton micans, Dimer, Monomer, Prostate cancer, Seco-ent-kaurene, synergism, Tumor therapyAutores:Alírica Isabel Suárez, Arvelo F.A., Chavez K., Sojo F.J., Vivas J.Fuentes:scopusCytotoxic, antioxidant and antimicrobial properties of red sweet pepper (Capsicum annuum L. var. Llanerón) extracts: In vitro study
ArticleAbstract: Alcoholic and aqueous extracts were obtained from red sweet pepper (Capsicum annuum L.) by differentPalabras claves:Antimicrobial, antioxidant, CAPSICUM ANNUUM L., Cytotoxic, Red sweet pepperAutores:Alírica Isabel Suárez, Arvelo F.A., Calderón-Gabaldón M., Mosqueda-Melgar J., Raybaudi-Massilia R., Sojo F.J., Zambrano A.Fuentes:scopusNew cytotoxic isoflavone from the root bark of Brosimum utile
ArticleAbstract: A new isoflavone 5,7,4′-trihydroxy-3′-(3-hydroxy-3-methylbutyl)isoflavone (isowigtheone hydrate) (1)Palabras claves:Brosimum utile, Cytotoxic, Isiowigtheone hydrate, Isoflavone, MoraceaeAutores:Alírica Isabel Suárez, Arvelo F.A., Compagnone R.S., Delle Monache F., Ferrari F.Fuentes:scopusThe marine sponge toxin agelasine B increases the intracellular Ca <sup>2+</sup> concentration and induces apoptosis in human breast cancer cells (MCF-7)
ArticleAbstract: Purpose: In search for new drugs derived from natural products for the possible treatment of cancer,Palabras claves:Agelasine B, calcium, Natural products, SERCA, ThapsigarginAutores:Alírica Isabel Suárez, Arvelo F.A., Benaím G., Chirino P., Colman L., Compagnone R.S., de Sanctis J.B., Dipolo R., Felibertt P., Galindo-Castro I., Mayora A., Pimentel A.A., Rojas H., Silva M.L., Sojo F.J.Fuentes:scopusThe natural diterpene ent-16β-17α-dihydroxykaurane down-regulates Bcl-2 by disruption of the Ap-2α/Rb transcription activating complex and induces E2F1 up-regulation in MCF-7 cells
ArticleAbstract: ent-Kauranes are diterpene-type compounds commonly found in most plant species, especially from thePalabras claves:AP-2α/Rb, apoptosis, BCL-2, E2F1, ent-16β-17α-Dihydroxykaurane (DHK), PUMAAutores:Alírica Isabel Suárez, Álvarez A., Arvelo F.A., Compagnone R.S., Galindo-Castro I., Morales A.Fuentes:scopusThree new glutarimide alkaloids from Croton cuneatus
ArticleAbstract: Analysis of the dichloromethane extract of the aerial parts of Croton cuneatus led to the isolationPalabras claves:alkaloids, Croton cuneatus, Cytotoxic, euphorbiaceaeAutores:Alírica Isabel Suárez, Arvelo F.A., Blanco Z., Compagnone R.S., Delle Monache F.Fuentes:scopus