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Association between +45t>g adiponectin polymorphism gene and type 2 diabetes mellitus and metabolic syndrome in a venezuelan population [version 1; peer review: 2 approved, 1 approved with reservations]
ArticleAbstract: Background: Adiponectin (ADIPOQ) is a hormone primarily synthesized by adipocytes and encoded by thePalabras claves:ADIPOQ gene, DNA, Metabolic syndrome, polymorphism, Type 2 Diabetes mellitusAutores:Carem Prieto, D'addosio R., Hoedebecke K., Medina M.T., Mujica E., Parra M., Rodriguez J.E., Sánchez M.P., Valencia E., Valmore Bermúdez, Vergara K., Villalobos E.Fuentes:scopusAssociation of PPARγ2 GENE Pro12Ala allelic variant with obesity and metabolic syndrome components in a population of Maracaibo
ArticleAbstract: Introduction: In this study the association of rs1801282 allelic variant, g. 68777C G (Pro12Ala) ofPalabras claves:Metabolic syndrome, obesity, PPARγ2, Pro12Ala, Rs1801282Autores:Arráiz N., Carem Prieto, Marcucci R., Marín E., Mújica A., Mujica E., Perez D., Ramos M., Rojas-Quintero J., Sánchez M.P., Urdaneta B., Valmore BermúdezFuentes:scopusAllelic variant UCP3-55CT gene in obese individuals with and without anthropometric and metabolic alterations in Maracaibo municipality, Zulia state
ArticleAbstract: Background: The accumulation of body fat has a genetic basis. Given the importance of UCP3 in the rePalabras claves:-55C/T variant, Anthropometric abnormalities, Metabolic abnormalities, obesity, Rs1800849, UCP3Autores:Arráiz N., Camacho M., Carem Prieto, Joselyn Zula, Levy A., Marcucci R., Marín E., Mújica A., Mujica E., Rojas-Quintero J., Urdaneta B., Valmore Bermúdez, Vivas M.Fuentes:googlescopusMutations in the coding region of dominium of union of apoliprotein B-100: Diagnosis of apoliprotein B familiar defect
ArticleAbstract: Hypercholesterolemia is a risk factor for cardiovascular disease. Alterations in the genes encodingPalabras claves:ApoB-100, Arg3480Pro mutation, Familial defective apolipoprotein B, hypercholesterolemiaAutores:Añez-Ramos R., Arráiz N., Bello L.M., Carem Prieto, Escalona C., González M.C., Joselyn Zula, Mújica A., Mujica E., Pacheco M., Roque W., Toledo A.C., Valmore BermúdezFuentes:googlescopusNovel mutations identification in exon 4 of LDLR gene in patients with moderate hypercholesterolemia in a venezuelan population
ArticleAbstract: Familial hypercholesterolemia (FH) is an autosomal dominant disease characterized by increase in lowPalabras claves:Coronary artery disease, Familial hypercholesterolemia, Frameshift mutations, LDL-receptor, PCR-SSCPAutores:Arráiz N., Borjas L., Carem Prieto, Mujica E., Reyes F., Reyna-Villasmil N., Rondón N., Solís E., Valmore Bermúdez, Velasco M.Fuentes:googlescopus