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Nano-drug-based Targeted Therapy Alleviates Ferroptosis-induced Liver Toxicity
ReviewAbstract: Iron is an essential inorganic element for an organism, with several metabolic activities. The glycoPalabras claves:Cancer stem cells, Ferritin, ferroptosis, hemochromatosis, Oxidative Stress, Targeted therapyAutores:Chittineedi P., Hamad Sharif Shaik, JUAN ALEJANDRO NEIRA MOSQUERA, Mohiddin Gooty Jaffer, Pandrangi S.L., Sungey Naynee Sánchez LLagunoFuentes:scopusDown-Regulation of Cysteine-Glutamate Antiporter in ALDH1A1 Expressing Oral and Breast Cancer Stem Cells Induced Oxidative Stress-Triggered Ferroptosis
ArticleAbstract: Background: Sulfasalazine, an xCT inhibitor, is being used as a repurposed antineoplastic drug to inPalabras claves:ALDH1A1, Cancer stem cells, Cysteine-Glutamate Antiporter, Ferritin, ferroptosisAutores:Chittineedi P., JUAN ALEJANDRO NEIRA MOSQUERA, Mohiddin Gooty Jaffer, Pandrangi S.L., Ravi Shankar Bellala, Sungey Naynee Sánchez LLagunoFuentes:scopusAqueous Nyctanthes arbortristis and doxorubicin conjugated gold nanoparticles synergistically induced mTOR-dependent autophagy-mediated ferritinophagy in paclitaxel-resistant breast cancer stem cells
ArticleAbstract: Aim: Nyctanthes arbortristis Linn is a potential anti-diabetic drug that reduces glucose levels by dPalabras claves:Cancer stem cells, Drug resistance, ferritinophagy, Insulin, mTORAutores:Chittineedi P., JUAN ALEJANDRO NEIRA MOSQUERA, Mohiddin Gooty Jaffer, Pandrangi S.L., Sungey Naynee Sánchez LLagunoFuentes:scopusRole of Intracellular Iron in Switching Apoptosis to Ferroptosis to Target Therapy-Resistant Cancer Stem Cells
ReviewAbstract: Iron is a crucial element required for the proper functioning of the body. For instance, hemoglobinPalabras claves:apoptosis, Cancer stem cells, Drug resistance, ferroptosisAutores:Chalumuri S.S., Chittineedi P., JUAN ALEJANDRO NEIRA MOSQUERA, Meena A.S., Mohammad A., Mohiddin Gooty Jaffer, Pamuru R.R., Pandrangi S.L., Sungey Naynee Sánchez LLagunoFuentes:googlescopus