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Broadly neutralizing aptamers to SARS-CoV-2: A diverse panel of modified DNA antiviral agents
ArticleAbstract: Since its discovery, COVID-19 has rapidly spread across the globe and has had a massive toll on humaPalabras claves:aptamer, covid-19, modified DNA, MT: Oligonucleotides, SARS-COV-2, SELEX, Therapies and Applications, variants of concern, viral neutralizationAutores:Chadwick J., Chase C.N., Gelinas A.D., Harding A.C., James W.S., Janjic N., Javier Gilbert Jaramillo, Lee T., Liu S., Otis M.R., Ream B.E., Schneider D.J., Tan T.K., Zhang C.Fuentes:scopusErratum: Breadth and function of antibody response to acute SARS-CoV-2 infection in humans (PLoS Pathog (2021) 17:2 (e1009352) DOI: 10.1371/journal.ppat.1009352)
OtherAbstract: There is an error in the caption for S2 Fig.The cells in this experiment were transduced to expressPalabras claves:Autores:Chen C.P., Chen T.H., Cheng C.Y., Cheng S.H., Daniels R.S., Harding A.C., Harvey R., Huang C.G., Huang K.Y.A., Huang Y.C., Hussain S., James W.S., Jan J.T., Javier Gilbert Jaramillo, Knight M.L., Lin T.Y., Lin Y.C., Liu X., Ma C., McCauley J.W., Rijal P., Schimanski L., Shih S.R., Tan T.K., Townsend A.R.Fuentes:scopusNeutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago
ArticleAbstract: Combinatorial antibody libraries not only effectively reduce antibody discovery to a numbers game, bPalabras claves:Autores:Dwek R.A., Harding A.C., Huang X., James W.S., Javier Gilbert Jaramillo, Ji Q., Lee C.C.D., Lerner R.A., Li T., Li Y., Li Z., Liu H., Liu L., Ma P., Min C., Qiang M., Saxena A., Shi X., Tao P., Wang F., Wang H., Wang X., Wilson I.A., Wu N.C., Yang G., Yuan M., Zhang C., Zhang Y., Zhu X.Fuentes:scopusInclusion of cGAMP within virus-like particle vaccines enhances their immunogenicity
ArticleAbstract: Cyclic GMP-AMP (cGAMP) is an immunostimulatory molecule produced by cGAS that activates STING. cGAMPPalabras claves:cGAMP, Influenza a virus, SARS-COV-2, type I interferon, viral vaccine vectorAutores:Beveridge R., Borrow P., Bridgeman A., Chauveau L., Drakesmith H., Frost J.N., Javier Gilbert Jaramillo, Knight M.L., Liu X., Partridge T., Pedroza-Pacheco I., Rehwinkel J., Rijal P., Russell R.A., Tan T.K., Townsend A.R.Fuentes:scopusImmunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine
ArticleAbstract: Extension of the interval between vaccine doses for the BNT162b2 mRNA vaccine was introduced in thePalabras claves:antibody, B cell, BNT162b2, covid-19, dosing interval, Neutralization, SARS-COV-2, T cell, Vaccine, variants of concernAutores:Abuelgasim H., Adele S., Adland E., Adlou S., Akther H.D., Al-Taei S., Alhussni A., Ali M., Altmann T., Amini A., Angyal A., Arancibia-Cárcamo C.V., Austin J.A., Azim Ansari M., Barnes E., Bayley M., Bridges-Webb A., Brown A., Brown H., Brown R., Carroll M.W., Chalk J., Chand M., Chawla A., Chinnakannan S., Conlon C.P., Cross A., Cutteridge J., de Lara C., de Silva T.I., Deeks A.S., Dejnirattisai W., Denly L., Diffey B., Dimitriadis S., Dobson S.L., Dold C., Donnison T., Drake T.M., Dunachie S.J., Duncan C.J.A., Dupont M., Eyre D.W., Fairman A., Faustini S., Foulkes S., Frater J., Gardiner S., Gillson N., Goulder P., Hackstein C.P., Hall V., Hambleton S., Haniffa M., Hargreaves A., Haworth J., Hering L.M., Holmes J., Hopkins S., Horner E., Hornsby H., Jämsén A., Javier Gilbert Jaramillo, Jeffery K., Johnson S.A., Jones C., Kasanyinga M., Kelly S., Kilby J.A., Kirk R., Klenerman P., Knight M.L., Lawrie A., Lee L., Linder A., Longet S., Malone T., Matthews P.C., Meardon N., Mongkolsapaya J., Moore S.C., Nicols A.R., Payne R.P., Phillips E., Pollard A.J., Reyes L.S., Richter A., Rowland-Jones S.L., Saei A., Sandhar G., Screaton G.R., Shields A., Skelly D.T., Stafford L., Supasa P., Tipton T., Turtle L., Tyerman J.K., Whitham R., Wootton D.G.Fuentes:scopusKetotherapeutics for neurodegenerative diseases
Book PartAbstract: Alzheimer's disease (AD) and Parkinson's disease (PD) are, respectively, the most prevalent and fastPalabras claves:Alzheimer's disease, D-β-hydroxybutyrate, inflammation, Insulin, Ketone bodies, Ketone ester, Microglia, Mitochondria, Oxidative Stress, Parkinson's DiseaseAutores:Clarke K., Javier Gilbert Jaramillo, Norwitz N.G., Soto A.Fuentes:scopusTwo doses of SARS-CoV-2 vaccination induce robust immune responses to emerging SARS-CoV-2 variants of concern
ArticleAbstract: The extent to which immune responses to natural infection with severe acute respiratory syndrome corPalabras claves:Autores:Abuelgasim H., Adele S., Adland E., Adlou S., Alhussni A., Ali M., Amini A., Barnes E., Blackwell L., Bridges-Webb A., Brown A., Brown H., Camara S., Carroll M.W., Cassar M.P., Chinnakannan S., Conlon C.P., Csala A., Cutteridge J., de Lara C., de Oliveira T., de Silva T.I., Deeks A.S., Denly L., Dimitriadis S., Dold C., Dong T., Donnison T., Dunachie S.J., Duncan C.J.A., Edmans M., Frater J., Fries A., Goulder P., Hackstein C.P., Harding A.C., Hill J., Ho L.P., Holmes J., Huang K.Y.A., Hutchings C.L., James W.S., Javier Gilbert Jaramillo, Jay C., Jeffery K., Johnson S.A., Kasanyinga M., Kerneis S., Klenerman P., Knight J.C., Knight M.L., Lee L.N., Li W., Lillie K., Linder A., Longet S., Malone T., Marinou S., Marjot T., Matthews P.C., Mehta H., Mentzer A.J., Moore S.C., Neubauer S., Ogbe A., O’Donnell D., Pace M., Payne R.P., Peng Y., Petousi N., Phalora P., Phillips E., Pollard A.J., Raman B., Richter A., Rijal P., Robinson N., Rongkard P., Schimanski L., Sigal A., Silva-Reyes L., Simmons B., Skelly D.T., Stafford L., Talbot N.P., Tan T.K., Thomas S.R., Tipoe T., Tipton T., Townsend A.R., Turtle L., Watson A.J.R., Weeks E., Wilson R., Zacharopoulou P.Fuentes:scopusThe ketogenic diet and remission of psychotic symptoms in schizophrenia: Two case studies
ArticleAbstract:Palabras claves:diet, Ketogenic, Ketones, Ketosis, Schizoaffective, SchizophreniaAutores:Javier Gilbert Jaramillo, Palmer C.M., Westman E.C.Fuentes:scopus