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Plant Biotechnology(3)
Frontiers in Plant Science(2)
Biotechnology and Bioengineering(1)
Fifty Years of Cytochrome P450 Research(1)
Journal of Natural Medicines(1)
Combinatorial biosynthesis of legume natural and rare triterpenoids in engineered yeast
ArticleAbstract: Triterpenoid saponins are a diverse group of specialized (secondary) metabolites with many biologicaPalabras claves:4-epi-hederagenin, Combinatorial biosynthesis, CYP72A, cytochrome P450 monooxygenase, Gypsogenic acid, Medicago truncatula, Soyasapogenol BAutores:Ery Odette Fukushima, Muranaka T., Ohyama K., Saito K., Sawai S., Seki H., Suzuki M.Fuentes:googlescopusComparative Analysis of NADPH-Cytochrome P450 Reductases From Legumes for Heterologous Production of Triterpenoids in Transgenic Saccharomyces cerevisiae
ArticleAbstract: Triterpenoids are plant specialized metabolites with various pharmacological activities. They are wiPalabras claves:cytochrome P450 monooxygenases (CYP), heterologous production, Legumes, NADPH-cytochrome P450 reductases (CPR), Saccharomyces Cerevisiae, TriterpenoidsAutores:Chikugo A., Ery Odette Fukushima, Istiandari P., Muranaka T., Seki H., Srisawat P., Suzuki H., Tamura K., Yasumoto S.Fuentes:googlescopusComparative analysis of CYP716A subfamily enzymes for the heterologous production of C-28 oxidized triterpenoids in transgenic yeast
ArticleAbstract: Several enzymes of the CYP716A subfamily have been reported to be involved in triterpenoid biosynthePalabras claves:Beta Vulgaris, Coffea Arábica, CYP716A, Olea europaea, TriterpenoidAutores:Ery Odette Fukushima, Muranaka T., Ohyama K., Seki H., Suzuki H., Umemoto N.Fuentes:googlescopusArtemisinin-based antimalarial research: application of biotechnology to the production of artemisinin, its mode of action, and the mechanism of resistance of Plasmodium parasites
ReviewAbstract: Malaria is a worldwide disease caused by Plasmodium parasites. A sesquiterpene endoperoxide artemisiPalabras claves:Artemisia annua, Artemisinin, MALARIA, Metabolic engineering, Mode of action, Resistant parasitesAutores:Ery Odette Fukushima, Muangphrom P., Muranaka T., Seki H.Fuentes:googlescopusFunctional analysis of orthologous artemisinic aldehyde Δ11(13)-reductase reveals potential artemisinin-producing activity in non-artemisinin-producing Artemisia absinthium
ArticleAbstract: Artemisinin is the most effective antimalarial compound isolated from Artemisia annua. Artemisinic aPalabras claves:ARTEMISIA ABSINTHIUM, Artemisinin, DBR2 ortholog, Dihydroartemisinic aldehyde, ReductaseAutores:Ery Odette Fukushima, Muangphrom P., Muranaka T., Seki H., Suzuki M.Fuentes:googlescopusHeterologous expression of triterpene biosynthetic genes in yeast and Subsequent Metabolite Identification Through GC-MS
ArticleAbstract: Heterologous expression of plant metabolic enzymes in microorganisms is extensively used for identifPalabras claves:2, 3-Oxidosqualene, Combinatorial biosynthesis, Cytochrome P450 monooxygenases (CYPs), Cytochrome P450 reductase (CPR), Oxidosqualene cyclases (OSCs), Triterpenoid, Triterpenol, YeastAutores:Ery Odette Fukushima, Muranaka T., Seki H.Fuentes:googlescopusHigh-yield bioactive triterpenoid production by heterologous expression in Nicotiana benthamiana using the Tsukuba system
ArticleAbstract: Oleanolic acid is a pentacyclic triterpenoid found in numerous plant species and is a precursor to sPalabras claves:CYP716A12, Nicotiana benthamiana, oleanolic acid, plant-specialized metabolites, transient protein expression, TriterpenoidsAutores:Ery Odette Fukushima, Miura K., Muranaka T., Romsuk J., Seki H., Yasumoto S.Fuentes:googlescopusIdentification and characterization of a novel sesquiterpene synthase, 4-amorphen-11-ol synthase, from artemisia maritima
ArticleAbstract: Artemisinin, a sesquiterpene lactone exhibiting effective antimalarial activity, is produced by onlyPalabras claves:4-amorphen-11-ol, 4-amorphen-11-ol synthase, Artemisia maritima, Artemisinin, Sesquiterpene synthaseAutores:Ery Odette Fukushima, Matsumoto S., Muangphrom P., Muranaka T., Nishiwaki M., Seki H.Fuentes:googlescopusTriterpene functional genomics in licorice for identification of CYP72A154 involved in the biosynthesis of glycyrrhizin
ArticleAbstract: Glycyrrhizin, a triterpenoid saponin derived from the underground parts of Glycyrrhiza plants (licorPalabras claves:Autores:Akashi T., Aoki T., Ery Odette Fukushima, Mizutani M., Muranaka T., Ohnishi T., Ohyama K., Saito K., Sawai S., Seki H., Sudo H.Fuentes:googlescopusProduction of the bioactive plant-derived triterpenoid morolic acid in engineered Saccharomyces cerevisiae
ArticleAbstract: Morolic acid is a plant-derived triterpenoid that possesses pharmacological properties such as cytotPalabras claves:GEV chimeric transcription factor, Metabolic engineering, morolic acid, Saccharomyces Cerevisiae, TriterpenoidAutores:Ery Odette Fukushima, Muranaka T., Robertlee J., Seki H., Srisawat P., Yasumoto S.Fuentes:googlescopus