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scopus(14)
4(1H)-quinolones with liver stage activity against Plasmodium berghei
ArticleAbstract: With the exception of primaquine, tafenoquine, and atovaquone, there are very few antimalarials thatPalabras claves:Autores:Cross R.M., Fabián E. Sáenz, Kyle D.E., Lacrue A.N., Manetsch R., Monastyrskyi A., Mutka T.S., Stein S., Udenze K.O.Fuentes:googlescopus4-(1H)-quinolones and 1,2,3,4-tetrahydroacridin-9(10H)-ones prevent the transmission of Plasmodium falciparum to Anopheles freeborni
ArticleAbstract: Malaria kills approximately 1 million people a year, mainly in sub-Saharan Africa. Essential steps iPalabras claves:Autores:Cross R.M., Fabián E. Sáenz, Kyle D.E., Lacrue A.N., Maignan J.R., Manetsch R., Udenze K.O.Fuentes:googlescopusGenotypes and phenotypes of resistance in Ecuadorian Plasmodium falciparum
ArticleAbstract: Background: Malaria continues to be endemic in the coast and Amazon regions of Ecuador. Clarifying cPalabras claves:ECUADOR, Genotypes, MALARIA, Phenotypes, Plasmodium falciparum, RESISTANCEAutores:Castro L.E., Claudia A. Vera-Arias, Fabián E. Sáenz, Gabriela Valenzuela, Rohrbach P., Valencia-Zamora J.Fuentes:googlescopusEvidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model
ArticleAbstract: The increasing prevalence in Southeast Asia of Plasmodium falciparum infections with delayed parasitPalabras claves:Autores:Cremers S., Fabián E. Sáenz, Fidock D.A., Henrich P.P., Kyle D.E., O'Brien C.Fuentes:googlescopusDiverse origin of Plasmodium falciparum in northwest Ecuador
ArticleAbstract: Background: Ecuador plans to eliminate malaria by 2020, and the country has already seen a decreasePalabras claves:ECUADOR, Genetic structure, MALARIA, microsatellites, Plasmodium falciparumAutores:Castro L.E., Claudia A. Vera-Arias, Fabián E. Sáenz, Gómez-Obando J.Fuentes:googlescopusNovel 4-aminoquinoline analogs highly active against the blood and sexual stages of Plasmodium in vivo and in vitro
ArticleAbstract: New drugs to treat malaria must act rapidly and be highly potent against asexual blood stages, wellPalabras claves:Autores:Fabián E. Sáenz, Kyle D.E., Mutka T.S., Oduola A.M.J., Udenze K.O.Fuentes:googlescopusHigh-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion typing by digital PCR to monitor malaria rapid diagnostic test efficacy
ArticleAbstract: Most rapid diagnostic tests for Plasmodium falciparum malaria target the Histidine-Rich Proteins 2 aPalabras claves:Autores:Abdul-Hakim M., Afrane Y., Ali A., Badu K., Claudia A. Vera-Arias, Fabián E. Sáenz, Fakih B.S., Ferreira M.U., Hetzel M.W., Holzschuh A., Kazura J.W., Koepfli C., Ladeia-Andrade S., Oduma C.O., Yan G., Yewhalaw D., Yukich J., Zemene E.Fuentes:googlescopusOrally bioavailable 6-chloro-7-methoxy-4(1 H)-quinolones efficacious against multiple stages of plasmodium
ArticleAbstract: The continued proliferation of malaria throughout temperate and tropical regions of the world has prPalabras claves:Autores:Bathurst I., Burrows J.N., Charman S.A., Cross R.M., Fabián E. Sáenz, Flanigan D.L., Fronczek F.R., Guida W.C., Kyle D.E., Lacrue A.N., Maignan J.R., Manetsch R., Monastyrskyi A., Mutka T.S., Shackleford D.M., White K.L., Wojtas L.Fuentes:googlescopusMalaria epidemiology in low-endemicity areas of the northern coast of Ecuador: High prevalence of asymptomatic infections
ArticleAbstract: Background: The recent scale-up in malaria control measures in Latin America has resulted in a signiPalabras claves:Asymptomatic malaria, ECUADOR, Elimination, Knowledge attitude and practicesAutores:Alvarez A., Andrea Arévalo-Cortés, Andrea C. Poveda-Loayza, Arévalo-Herrera M., Benavides Y., Castellanos A., Castro L.E., Fabián E. Sáenz, Gabriela Valenzuela, Gutierrez J.B., Herrera S., Vallejo A.F., Yan Y.H.Fuentes:googlescopusQuinolone-3-diarylethers: A new class of antimalarial drug
ArticleAbstract: The goal for developing new antimalarial drugs is to find a molecule that can target multiple stagesPalabras claves:Autores:Angulo-Barturen I., Avery V.M., Bathurst I., Burrows J.N., Charman S.A., Cross R.M., Delves M.J., Duffy S., Fabián E. Sáenz, Ferrer S., Forquer I.P., Gamo F.J., Guy R.K., Herreros E., Jiménez-Díaz M.B., Kelly J.X., Kocken C.H.M., Kyle D.E., Lacrue A.N., Li Y., Manetsch R., Marfurt J., Mather M.W., Morrisey J.M., Mutka T.S., Nilsen A., Noviyanti R., Price R.N., Riscoe M.K., Ryan E., Sanz L.M., Sebayang B.F., Shackleford D.M., Siegl P., Sinden R.E., Steuten J., Vaidya A.B., White K.L., Winter R.W., Wirjanata G., Zeeman A.M.Fuentes:googlescopus