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4(1H)-quinolones with liver stage activity against Plasmodium berghei
ArticleAbstract: With the exception of primaquine, tafenoquine, and atovaquone, there are very few antimalarials thatPalabras claves:Autores:Cross R.M., Fabián E. Sáenz, Kyle D.E., Lacrue A.N., Manetsch R., Monastyrskyi A., Mutka T.S., Stein S., Udenze K.O.Fuentes:googlescopus4-(1H)-quinolones and 1,2,3,4-tetrahydroacridin-9(10H)-ones prevent the transmission of Plasmodium falciparum to Anopheles freeborni
ArticleAbstract: Malaria kills approximately 1 million people a year, mainly in sub-Saharan Africa. Essential steps iPalabras claves:Autores:Cross R.M., Fabián E. Sáenz, Kyle D.E., Lacrue A.N., Maignan J.R., Manetsch R., Udenze K.O.Fuentes:googlescopusDiverse origin of Plasmodium falciparum in northwest Ecuador
ArticleAbstract: Background: Ecuador plans to eliminate malaria by 2020, and the country has already seen a decreasePalabras claves:ECUADOR, Genetic structure, MALARIA, microsatellites, Plasmodium falciparumAutores:Castro L.E., Claudia A. Vera-Arias, Fabián E. Sáenz, Gómez-Obando J.Fuentes:googlescopusGenotypes and phenotypes of resistance in Ecuadorian Plasmodium falciparum
ArticleAbstract: Background: Malaria continues to be endemic in the coast and Amazon regions of Ecuador. Clarifying cPalabras claves:ECUADOR, Genotypes, MALARIA, Phenotypes, Plasmodium falciparum, RESISTANCEAutores:Castro L.E., Claudia A. Vera-Arias, Fabián E. Sáenz, Gabriela Valenzuela, Rohrbach P., Valencia-Zamora J.Fuentes:googlescopusHigh-throughput Plasmodium falciparum hrp2 and hrp3 gene deletion typing by digital PCR to monitor malaria rapid diagnostic test efficacy
ArticleAbstract: Most rapid diagnostic tests for Plasmodium falciparum malaria target the Histidine-Rich Proteins 2 aPalabras claves:Autores:Abdul-Hakim M., Afrane Y., Ali A., Badu K., Claudia A. Vera-Arias, Fabián E. Sáenz, Fakih B.S., Ferreira M.U., Hetzel M.W., Holzschuh A., Kazura J.W., Koepfli C., Ladeia-Andrade S., Oduma C.O., Yan G., Yewhalaw D., Yukich J., Zemene E.Fuentes:googlescopusEvidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model
ArticleAbstract: The increasing prevalence in Southeast Asia of Plasmodium falciparum infections with delayed parasitPalabras claves:Autores:Cremers S., Fabián E. Sáenz, Fidock D.A., Henrich P.P., Kyle D.E., O'Brien C.Fuentes:googlescopusTargeted disruption of maebl in Plasmodium falciparum
ArticleAbstract:Palabras claves:Erythrocyte binding protein, Invasion assays, MAEBL, MALARIA, Plasmodium falciparumAutores:Adams J.H., Balu B., Blair P., Cowman A., Fabián E. Sáenz, Fu J., Reed M., Singh N.Fuentes:googlescopusThe Relative Role of Climate Variation and Control Interventions on Malaria Elimination Efforts in El Oro, Ecuador: A Modeling Study
ArticleAbstract: Malaria is a vector-borne disease of significant public health concern. Despite widespread success oPalabras claves:Climate, Elimination, Environmental change, MALARIA, spatio-temporal model, Vector controlAutores:Anna M. Stewart-Ibarra, Carrasco-Escobar G., Drakeley C., Efraín Felix Beltrán Ayala, Fabián E. Sáenz, Fletcher I.K., Jefferson Adrian, Jones K.E., Lowe R., Ordoñez T., Silva M., Sippyid R.Fuentes:googlescopusThe transmembrane isoform of Plasmodium falciparum MAEBL is essential for the invasion of Anopheles salivary glands
ArticleAbstract: Malaria transmission depends on infective stages in the mosquito salivary glands. Plasmodium sporozoPalabras claves:Autores:Adams J.H., Balu B., Fabián E. Sáenz, Mendonca S.R., Smith J.Fuentes:googlescopusNovel 4-aminoquinoline analogs highly active against the blood and sexual stages of Plasmodium in vivo and in vitro
ArticleAbstract: New drugs to treat malaria must act rapidly and be highly potent against asexual blood stages, wellPalabras claves:Autores:Fabián E. Sáenz, Kyle D.E., Mutka T.S., Oduola A.M.J., Udenze K.O.Fuentes:googlescopus