Mostrando 10 resultados de: 14
Filtros aplicados
Publisher
Journal of Allergy and Clinical Immunology(3)
Journal of Experimental Medicine(2)
Nature Immunology(2)
Arthritis and Rheumatology(1)
Brain(1)
Área temáticas
Enfermedades(13)
Fisiología humana(7)
Farmacología y terapéutica(4)
Anatomía humana, citología, histología(2)
Bioquímica(2)
Origen
scopus(14)
Author Correction: The cellular composition of the human immune system is shaped by age and cohabitation (Nature Immunology, (2016), 17, 4, (461-468), 10.1038/ni.3371)
OtherAbstract: In the version of this article initially published, in the Acknowledgements, the grant number for thPalabras claves:Autores:Boeckxstaens G., Carr E.J., Dooley J., Goris A., Josselyn E. Garcia-Perez, Lagou V., Lee J.C., Linterman M.A., Liston A., Meyts I., Wouters C.H.Fuentes:scopusA kindred with mutant IKAROS and autoimmunity
ArticleAbstract:Palabras claves:Autores:Claessens F., Dooley J., Frietze S., Gijsbers R., Helsen C., Humblet-Baron S., Josselyn E. Garcia-Perez, Liston A., Meyts I., Rodriguez P.D., Schjerven H., Schlenner S.M., van der Burg M., Van Nieuwenhove E., van Schouwenburg P.A., Verhoeyen E., Wouters C.H.Fuentes:scopusA novel human IL2RB mutation results in T and NK cell–driven immune dysregulation
ArticleAbstract: The pleiotropic actions of interleukin-2 (IL-2) are essential for regulation of immune responses andPalabras claves:Autores:Baxter R.M., Black J., Blish C.A., Dawany N., de Zoeten E.F., Dutmer C.M., Eissa H., Fernandez I.Z., Galambos C., Gumbart J.C., Hsieh E.W.Y., Josselyn E. Garcia-Perez, Kedl R.M., Kelsen J.R., Kong D.S., Lundquist K., Nguyen T., Ogolla S., Quinones R., Ranganath T., Rochford R., Sullivan K.E., Vendrame E., Verneris M.R.Fuentes:scopusCorrection: A novel human IL2RB mutation results in T and NK cell–driven immune dysregulation (CMAJ (2019) 216, 6 (1255) DOI: 10.1084/jem.20182015)
OtherAbstract: The authors regret that in the original version of Fig. S2 G, the plot for healthy pediatric (H. PedPalabras claves:Autores:Baxter R.M., Black J., Blish C.A., Dawany N., de Zoeten E.F., Dutmer C.M., Eissa H., Fernandez I.Z., Galambos C., Gumbart J.C., Hsieh E.W.Y., Josselyn E. Garcia-Perez, Kedl R.M., Kelsen J.R., Kong D.S., Lundquist K., Nguyen T., Ogolla S., Quinones R., Ranganath T., Rochford R., Sullivan K.E., Vendrame E., Verneris M.R.Fuentes:scopusCytotoxic T-lymphocyte-associated protein 4-Ig effectively controls immune activation and inflammatory disease in a novel murine model of leaky severe combined immunodeficiency
ArticleAbstract: Background: Severe combined immunodeficiency can be caused by loss-of-function mutations in genes inPalabras claves:Artemis, cytotoxic T-lymphocyte-associated protein 4, immune dysregulation, Leaky severe combined immunodeficiency, regulatory T cellAutores:Baron F., Humblet-Baron S., Josselyn E. Garcia-Perez, Liston A., Pasciuto E., Schönefeldt S.Fuentes:scopusCTLA4 message reflects pathway disruption in monogenic disorders and under therapeutic blockade
ReviewAbstract: CTLA-4 is essential for immune tolerance. Heterozygous CTLA4 mutations cause immune dysregulation evPalabras claves:CTLA4, immunotherapy, Ipilimumab, LRBA, mRNAAutores:Baxter R.M., Dutmer C.M., Hsieh E.W.Y., Jordan M.B., Josselyn E. Garcia-Perez, Kong D.S., McCarter M., Routes J.M., Tobin R., Verbsky J.Fuentes:scopusAbnormal differentiation of B cells and megakaryocytes in patients with Roifman syndrome
ArticleAbstract: Background: Roifman syndrome is a rare inherited disorder characterized by spondyloepiphyseal dysplaPalabras claves:B cells, Platelets, RNA processing, Roifman syndromeAutores:Casteels I., Collin R., De Zegher F., Freson K., Greene D., Heremans J., Humblet-Baron S., Josselyn E. Garcia-Perez, Lesage S., Liston A., Matthys P., Meyts I., Penkett C.J., Put K., Schlenner S.M., Stirrups K., Thys C., Turro E., Van Geet C., Van Nieuwenhove E., Wouters C.H.Fuentes:scopusGenetic Architecture of Adaptive Immune System Identifies Key Immune Regulators
ArticleAbstract: The immune system is highly diverse, but characterization of its genetic architecture has lagged behPalabras claves:adaptive immune system, association, autoimmunity, Genetics, Genome-wide association, immune phenotype, susceptibilityAutores:Boeckxstaens G., Bowness P., Chen L., Dooley J., Dubois B., Goris A., Hilven K., Humblet-Baron S., Josselyn E. Garcia-Perez, Lagou V., Liston A., Mallants K., Moisse M., Prezzemolo T., Smets I., Van Damme P., Van Horebeek L., Vandebergh M.Fuentes:scopusFamilial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation
ArticleAbstract: Pyrin responds to pathogen signals and loss of cellular homeostasis by forming an inflammasome complPalabras claves:Autores:Amselem S., Baker P.J., Cochet E., Copin B., Dagley L.F., De Nardo D., De Somer L., Dooley J., Goris A., Holley C.L., Jeandel P.Y., Jéru I., Josselyn E. Garcia-Perez, Lagou V., Lawless D., Liston A., Lyras D., Masters S.L., Medlej-Hashim M., Megarbane A., Moghaddas F., Nicholson S.E., Parry D.A., Pasciuto E., Ruuth-Praz J., Savic S., Schroder K., Sciot R., Van Eyck L., Van Nieuwenhove E., Webb A.I., Wouters C.H.Fuentes:scopusMultiple sclerosis risk variants alter expression of co-stimulatory genes in B cells
ArticleAbstract: The increasing evidence supporting a role for B cells in the pathogenesis of multiple sclerosis promPalabras claves:B cells, CD40, CD86, Multiple Sclerosis, susceptibilityAutores:Ban M., Coles A.J., Compston A., Dooley J., Dubois B., Fiddes B., Goris A., He D., Humblet-Baron S., Jones J., Josselyn E. Garcia-Perez, Liao W., Liston A., Mallants K., Sawcer S., Smets I., Wang G.Fuentes:scopus