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Activation of the neuroprotective ERK signaling pathway by fructose-1,6-bisphosphate during hypoxia involves intracellular Ca<sup>2+</sup> and phospholipase C
ArticleAbstract: The mechanism of the neuroprotective action of the glycolytic pathway intermediate fructose-1,6-bispPalabras claves:6-Bisphosphate, Brain injury, CA1 neuron, calcium, Fructose-1, Hypoxia, ischemiaAutores:Bickler P.E., Fahlman C.S., George A. Gregory, Sullivan B.Fuentes:scopusFructose-1,6-bisphosphate after hypoxic ischemic injury is protective to the neonatal rat brain
ArticleAbstract: Fructose-1,6-bisphosphate (FBP) has been shown to attenuate central nervous system injury in adult aPalabras claves:Brain injury, Development, Hypocalcemia, Hypoxia, ischemia, neonate, therapyAutores:Berrios M., Ferriero D., George A. Gregory, Sheldon R., Sola A.Fuentes:scopusFructose-1,6-bisphosphate preserves intracellular glutathione and protects cortical neurons against oxidative stress
ArticleAbstract: Fructose-1,6-bisphosphate (FBP), an endogenous intermediate of glycolysis, protects the brain againsPalabras claves:6-Bisphosphate, Disorders of the nervous system, Fructose-1, Glutathione, Hypoxia, ischemia, Reactive oxygen speciesAutores:Christen S., Ferriero D., Francisco C., George A. Gregory, Manabat C., Täuber M., Vexler Z., Wong A.Fuentes:scopusFructose-1,6-bisphosphate reduces ATP loss from hypoxic astrocytes
ArticleAbstract: Hypoxia caused injury and metabolic dysfunction of astrocytes, as indicated by a time-dependent lossPalabras claves:Adenosine triphosphate, Astrocyte, cell culture, fructose-1,6-bisphosphate, HypoxiaAutores:Chan P.H., George A. Gregory, Welsh F., Yu A.Fuentes:scopusEffects of neuroprotective dose of fructose-1,6-bisphosphate on hypoxia-induced expression of c-fos and hsp70 mRNA in neonatal rat cerebrocortical slices
ArticleAbstract: In situ hybridization (ISH) measurements of c-fos and hsp70 expression were made in brain slice studPalabras claves:brain slice, c-fos, FBP (fructose-1,6-bisphosphate), hsp70, Hypoxia, neonateAutores:Chan P.H., Espanol M., George A. Gregory, Hasegawa K., Litt L., Sharp F.Fuentes:scopusNeuroprotection and intracellular Ca<sup>2+</sup> modulation with fructose-1,6-bisphosphate during in vitro hypoxia-ischemia involves phospholipase C-dependent signaling
ArticleAbstract: The neuroprotectant fructose-1,6-bisphosphate (FBP) preserves cellular [ATP] and prevents catastrophPalabras claves:Brain injury, CA1 neuron, Cacium, Fructose-1,6-bishopsphate, Hypoxia, ischemiaAutores:Bickler P.E., Donohoe P., Fahlman C.S., George A. Gregory, Vexler Z.Fuentes:scopusResponse of cerebral endothelial cells to hypoxia: modification by fructose-1,6-bisphosphate but not glutamate receptor antagonists
ArticleAbstract: Damage to the cerebral endothelium from ischemia could exacerbate brain injury by altering vascularPalabras claves:endothelial cell, fructose-1,6-bisphosphate, glutamate, Hypoxia, ischemia, MK-801Autores:Chan P.H., Chan T.Y.Y., George A. Gregory, Gobbel G.Fuentes:scopusProtection of astrocytes by fructose 1,6-bisphosphate and citrate ameliorates neuronal injury under hypoxic conditions
ArticleAbstract: Fructose 1,6-bisphosphate (FBP) protects astrocytes from hypoxic injury in vitro. To determine whethPalabras claves:citric acid, Co-culture, Fluorocitrate, Fructose 1,6- bisphosphate, Mixed culture, pentose phosphate pathwayAutores:Chan P.H., Chan T.Y.Y., George A. Gregory, Kelleher J.A.Fuentes:scopus