Mostrando 4 resultados de: 4
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Article(4)
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Bioorganic and Medicinal Chemistry Letters(1)
Current Topics in Medicinal Chemistry(1)
PLoS ONE(1)
Anti-inflammatory activity and cheminformatics analysis of new potent 2-substituted 1-methyl-5-nitroindazolinones
ArticleAbstract: After the identification of the anti-inflammatory properties of VA5-13l (2-benzyl-1- methyl-5-nitroiPalabras claves:Anti-inflammatory compound, Nitroindazolinones, SARANEA software, Structure-activity relationship, TPA-induced mouse ear edema, zebrafishAutores:Andújar I., Arán V.J., Crawford A.D., De Witte P.A.M., Díaz-Mendoza C., Giner R.M., Manjarrez G., María Lorena Cordero-Maldonado, Pérez-Jiménez F., Siverio-Mota D., Veítia M.S.I., Vicet-Muro L., Yovani Marrero-PonceFuentes:scopus2-Octadecynoic acid as a dual life stage inhibitor of Plasmodium infections and plasmodial FAS-II enzymes
ArticleAbstract: The malaria parasite Plasmodium goes through two life stages in the human host, a non-symptomatic liPalabras claves:2-Octadecynoic acid, Acetylenic fatty acids, Blood stage, Liver stage, MALARIA, plasmodium, Type II fatty acid synthaseAutores:Andricopulo A.D., Bwalya A.G., Carballeira N.M., Crawford A.D., Guido R.V.C., Itoe M.A., Kaiser M., María Lorena Cordero-Maldonado, Mota M.M., Tasdemir D.Fuentes:scopusIntegration of Microfractionation, qNMR and Zebrafish Screening for the In Vivo Bioassay-Guided Isolation and Quantitative Bioactivity Analysis of Natural Products
ArticleAbstract: Natural products (NPs) are an attractive source of chemical diversity for small-molecule drug discovPalabras claves:Autores:Bohni N., Crawford A.D., De Witte P.A.M., Esguerra C.V., Kamuhabwa A.R., Maes J., Marcourt L., María Lorena Cordero-Maldonado, Moshi M.J., Munck S., Siverio-Mota D., Wolfender J.L.Fuentes:rraaescopusIntegration of microfractionation, qNMR and zebrafish screening for the In vivo bioassay-guided isolation and quantitative bioactivity analysis of natural products
ArticleAbstract: Natural products (NPs) are an attractive source of chemical diversity for small-molecule drug discovPalabras claves:BIOENSAYO, PEZ CEBRAAutores:Alexander D. Crawford, Appolinary R. Kamuhabwa, Camila V. Esguerra, Dany Siverio Mota, Jan Maes, Jean-Luc Wolfender, Laurence Marcourt, Mainen J. Moshi, María Lorena Cordero-Maldonado, Nadine Bohni, Peter A. M. Witte, de, Sebastian MunckFuentes:rraae