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Cinnamomum sp. and Pelargonium odoratissimum as the Main Contributors to the Antibacterial Activity of the Medicinal Drink Horchata: A Study Based on the Antibacterial and Chemical Analysis of 21 Plants
ArticleAbstract: Horchata, a herbal infusion drink from Ecuador containing a mixture of medicinal plants, has been rePalabras claves:Antibacterial activity, biofilm, Cinnamomumsp, HORCHATA, Natural products, Pelargonium odoratissimumAutores:Antonio Machado, Diana Celi, Eduardo Tejera, José M. Alvarez-Suarez, Paulina Fernandez-SotoFuentes:scopusComputational modeling pbkp_redicts potential effects of the herbal infusion “horchata” against COVID-19
ArticleAbstract: Bioactive plant-derived molecules have emerged as therapeutic alternatives in the fight against thePalabras claves:covid-19, docking, Gene Ontology, Herbal infusion, Horchata infusion, molecular dynamics, SARS-COV-2Autores:Ana Lucía Noboa, Eduardo Tejera, Giampieri F., Gisselle Toscano, José M. Alvarez-Suarez, Valeria Ochoa-Herrera, Yunierkis Perez-CastilloFuentes:googlescopusAnti-inflammatory effect of the medicinal herbal mixture infusion, Horchata, from southern Ecuador against LPS-induced cytotoxic damage in RAW 264.7 macrophages
ArticleAbstract: The phytochemical composition and the antioxidant and anti-inflammatory activities of a mixture of 2Palabras claves:Anti-inflammatory capacity, ECUADOR, Herbal infusion, Herbal mixture, Horchata drink, Medicinal Plants, Phenolic profileAutores:Eduardo Tejera, Gabriel Iturralde, Gonzalez-Paramás A.M., José M. Alvarez-Suarez, Mabel Guevara, María G. Granda-Albuja, Santos-Buelga C., Silvana Granja-Albuja, Tatiana S. Jaramillo-VivancoFuentes:scopusA multi-objective approach for anti-osteosarcoma cancer agents discovery through drug repurposing
ArticleAbstract: Osteosarcoma is the most common type of primary malignant bone tumor. Although nowadays 5-year surviPalabras claves:Drug repositioning, Machine learning, Multi-objective model, Osteosarcoma, Virtual ScreeningAutores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Eduardo Tejera, Gabriela Fernanda Jaramillo-Koupermann, González‐díaz H., Munteanu C.R., Sierra A.P., Yunierkis Perez-CastilloFuentes:scopusA multi-objective approach for drug repurposing in preeclampsia
ArticleAbstract: Preeclampsia is a hypertensive disorder that occurs during pregnancy. It is a complex disease with uPalabras claves:Drugs repurposing, Machine learning, Multi-objective models, PreeclampsiaAutores:Alejandro Cabrera-Andrade, Andrea Chamorro, Eduardo Tejera, Sánchez M.E., Yunierkis Perez-CastilloFuentes:scopusDevelopment of a SNaPshot<sup>®</sup> Multiplex system for the typing of single nucleotide polymorphisms (SNPs) involved in the adaptive response to high altitude hypoxia
ArticleAbstract: HIF2-α is the leading gene involved in adaptive response to hypoxia. The codification of this gene rPalabras claves:Genotyping, Hypoxia, rs10187368, rs13419896, rs1867728, rs1867785, rs1868092, rs4953354, rs895436, SNaPshot, SNPAutores:Badin M., Camargo M., Cesar Paz-y-Miño, Eduardo Tejera, Germán Burgos, M. RuanoFuentes:scopusCritical Review of Plant-Derived Compounds as Possible Inhibitors of SARS-CoV-2 Proteases: A Comparison with Experimentally Validated Molecules
ReviewAbstract: Ever since coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, was declared a pandemic on MarPalabras claves:Autores:Diana Celi, Eduardo Tejera, Giampieri F., José M. Alvarez-Suarez, Paul Cueva, Yasel Guerra, Yunierkis Perez-CastilloFuentes:scopusDesirability-based multi-objective QSAR in drug discovery
ReviewAbstract: The adjustment of multiple criteria in hit-to-lead identification and lead optimization is a major aPalabras claves:Desirability theory, Drug Discovery, MOOP-DESIRE methodology, Multi-objective QSARAutores:Borges F., Dominguez E.R., Eduardo Tejera, Maykel Cruz-Monteagudo, Natalia Dias Soeiro Cordeiro M.Fuentes:scopusFrom flamingo dance to (desirable) drug discovery: a nature-inspired approach
ReviewAbstract: The therapeutic effects of drugs are well known to result from their interaction with multiple intraPalabras claves:Autores:Aminael Sánchez-Rodríguez, Borges F., Eduardo Tejera, Mangiatordi G.F., Maykel Cruz-Monteagudo, Medina-Franco J.L., Natalia Dias Soeiro Cordeiro M., Nicolotti O., Schürer S.C., Yunierkis Perez-CastilloFuentes:googlescopusGene prioritization, communality analysis, networking and metabolic integrated pathway to better understand breast cancer pathogenesis
ArticleAbstract: Consensus strategy was proved to be highly efficient in the recognition of gene-disease association.Palabras claves:Autores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Cesar Paz-y-Miño, Eduardo Tejera, González‐díaz H., Munteanu C.R., Sierra A.P., Stephen Jones Barigye, Yunierkis Perez-CastilloFuentes:googlescopus