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A desirability-based multi objective approach for the virtual screening discovery of broad-spectrum anti-gastric cancer agents
ArticleAbstract: Gastric cancer is the third leading cause of cancer-related mortality worldwide and despite advancesPalabras claves:Autores:Aminael Sánchez-Rodríguez, Borges F., Eduardo Tejera, Maykel Cruz-Monteagudo, Natalia Dias Soeiro Cordeiro M., Pham-The H., Thu H.L.T., Yunierkis Perez-CastilloFuentes:googlescopusA multi-objective approach for anti-osteosarcoma cancer agents discovery through drug repurposing
ArticleAbstract: Osteosarcoma is the most common type of primary malignant bone tumor. Although nowadays 5-year surviPalabras claves:Drug repositioning, Machine learning, Multi-objective model, Osteosarcoma, Virtual ScreeningAutores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Eduardo Tejera, Gabriela Fernanda Jaramillo-Koupermann, González‐díaz H., Munteanu C.R., Sierra A.P., Yunierkis Perez-CastilloFuentes:scopusGene prioritization through consensus strategy, enrichment methodologies analysis, and networking for osteosarcoma pathogenesis
ArticleAbstract: Osteosarcoma is the most common subtype of primary bone cancer, affecting mostly adolescents. In recPalabras claves:Communality analysis, early recognition, Gene prioritization, Osteosarcoma, pathogenesisAutores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Cesar Paz-y-Miño, Eduardo Tejera, Gabriela Fernanda Jaramillo-Koupermann, González‐díaz H., Munteanu C.R., Sierra A.P., Yunierkis Perez-CastilloFuentes:scopusGene prioritization, communality analysis, networking and metabolic integrated pathway to better understand breast cancer pathogenesis
ArticleAbstract: Consensus strategy was proved to be highly efficient in the recognition of gene-disease association.Palabras claves:Autores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Cesar Paz-y-Miño, Eduardo Tejera, González‐díaz H., Munteanu C.R., Sierra A.P., Stephen Jones Barigye, Yunierkis Perez-CastilloFuentes:googlescopusNFBTA: A potent cytotoxic agent against glioblastoma
ArticleAbstract: Piplartine (PPL), also known as piperlongumine, is a biologically active alkaloid extracted from thePalabras claves:Analogue, ANTICANCER, Antiglioblastoma therapy, Piper, PiplartineAutores:De Almeida R.N., Eduardo Tejera, Filho C.D.S.M.B., Nóbrega F.R., Ozdemir O., Sousa D.P.D., Turkez H., Yunierkis Perez-CastilloFuentes:googlescopusOncoOmics approaches to reveal essential genes in breast cancer: a panoramic view from pathogenesis to precision medicine
ArticleAbstract: Breast cancer (BC) is the leading cause of cancer-related death among women and the most commonly diPalabras claves:Autores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Cesar Paz-y-Miño, Eduardo Tejera, González‐díaz H., Munteanu C.R., Santiago Xavier Guerrero, Sierra A.P., Stephen Jones Barigye, Yunierkis Perez-CastilloFuentes:googlescopusMolecular Modeling and In Vitro Evaluation of Piplartine Analogs against Oral Squamous Cell Carcinoma
ArticleAbstract: Cancer is a principal cause of death in the world, and providing a better quality of life and reduciPalabras claves:alkaloid, ANTICANCER, antitumor, Cytotoxicity, Medicinal Plants, Natural products, Piper, PiplartineAutores:da Fonseca A.C.C., Eduardo Tejera, Machado T.Q., Robbs B.K., Silva R.H.N., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopusPbkp_rediction of breast cancer proteins involved in immunotherapy, metastasis, and RNA-binding using molecular descriptors and artificial neural networks
ArticleAbstract: Breast cancer (BC) is a heterogeneous disease where genomic alterations, protein expression deregulaPalabras claves:Autores:Alejandro Cabrera-Andrade, Andrés López-Cortés, Cesar Paz-y-Miño, Eduardo Tejera, Gonzáles-Díaz H., Munteanu C.R., Santiago Xavier Guerrero, Sierra A.P., Vázquez-Naya J.M., Yunierkis Perez-CastilloFuentes:googlescopusTheoretical pbkp_rediction of antiproliferative activity against murine leukemia tumor cell line (L1210). 3D-morse descriptor and its application in computational chemistry)
ArticleAbstract: Cancer is among the top ten causes of death in the world but in spite of the efforts of the pharmacePalabras claves:3D-MoRSE, anticancer activity, Indolocarbazoles derivatives, QSARAutores:García-Mera X., Natalia Dias Soeiro Cordeiro M., Perez González M., Rodríguez-Borges J.E., Ruiz R.M., Saíz-Urra L., Yunierkis Perez-CastilloFuentes:googlescopus