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Chronic substance P (NK1) receptor antagonist and conventional antidepressant treatment increases burst firing of monoamine neurones in the locus coeruleus
OtherAbstract: The mechanism of action of conventional antidepressants (e.g. imipramine) has been linked to modulatPalabras claves:Autores:Harrison CastroFuentes:googleClinical efficacy of benralizumab in patients with severe, uncontrolled eosinophilic asthma and nasal polyposis: pooled analysis of the SIROCCO and CALIMA trials
OtherAbstract: Methods This was a post-hoc pooled analysis of the Phase III SIROCCO (48 weeks; NCT01928771; Lancet.Palabras claves:Autores:Harrison CastroFuentes:googleComparing ultrasonic and breath-actuated jet nebulisers for sputum induction
OtherAbstract: Background: Sputum induction is an established non-invasive approach to assess airway inflammation.Palabras claves:Autores:Harrison CastroFuentes:googleComparison of the phenotype of NK1R−/− mice with pharmacological blockade of the substance P (NK 1) receptor in assays for antidepressant and anxiolytic drugs
OtherAbstract: The phenotype of NK1R−/− mice was compared with that of acute pharmacological blockade of the tachykPalabras claves:Autores:Harrison CastroFuentes:googleCompassion meditation for posttraumatic stress disorder in veterans: A randomized proof of concept study
OtherAbstract: There is considerable interest in developing complementary and integrative approaches for amelioratiPalabras claves:Autores:Harrison CastroFuentes:googleCompostos farmacêuticos.
OtherAbstract: C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring havingPalabras claves:Autores:Harrison CastroFuentes:googleAssessment of a rapid liquid-based cytology method for measuring sputum cell counts
OtherAbstract: Differential sputum cell counting is not widely available despite proven clinical utility in the manPalabras claves:Autores:Harrison CastroFuentes:googleAsthma exacerbations and inhaled corticosteroids
OtherAbstract: Sir—TW Harrison and colleagues (Jan 24, p 271) 1 examine the effects of doubling the dose of inhaledPalabras claves:Autores:Harrison CastroFuentes:googleAzacyclic compounds, processes for their preparation and pharmaceutical compositions containing them
OtherAbstract: 125000001997 phenyl group Chemical group data: image/svg+xml; base64, PD94bWwgdmVyc2lvbj0nMS4wJyBlbmPalabras claves:Autores:Harrison CastroFuentes:googleBenralizumab Reduces Asthma Worsening Episodes
OtherAbstract: Rationale: CompEx (Composite Endpoint for Exacerbations) was recently proposed as a novel endpoint oPalabras claves:Autores:Harrison CastroFuentes:google