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A new aspect of the antiproliferative action of peripheral-type benzodiazepine receptor ligands
ArticleAbstract: Ro 5-4864 (4-chlorodiazepam), PK 11195 (1-(2-chlorophenyl)-1,3-dihydro-1-methyl-propyl)isoquinolinePalabras claves:(Chinese hamster), Benzodiazepine, cell proliferation, LungAutores:Antoni Camins, Camarasa J., Diez-Fernandez C., Escubedo E., Pujadas E.Fuentes:scopusA novel rhein-huprine hybrid ameliorates disease-modifying properties in preclinical mice model of Alzheimer’s disease exacerbated with high fat diet
ArticleAbstract: Background: Alzheimer’s disease (AD) is characterized by a polyetiological origin. Despite the globaPalabras claves:Alzheimer’s disease, BACE1, BDNF, cognitive decline, dendritic spines, high-fat diet, neuroinflammation, Rhein-huprine hybrid, Tau, TLR4Autores:Antoni Camins, Auladell C., Bulló M., Cano A., Espinosa-Jimenez T., Ettcheto M., Folch J., Muñoz-Torrero D., Olloquequi J., Parcerisas A., Pont C., Sanchez-Lopez E., Verdaguer E.Fuentes:scopusA single dose of pirfenidone attenuates neuronal loss and reduces lipid peroxidation after kainic acid-induced excitotoxicity in the pubescent rat hippocampus
ArticleAbstract: Systemic administration of kainic acid (KA) in rodents triggers limbic seizures following selectivePalabras claves:4-Hydroxynonenal (4-HNE), Kainic Acid Model, Neurodegeneration, neuroprotection, PirfenidoneAutores:Antoni Camins, Armendáriz-Borunda J., Bañuelos-Pineda J., Castro-Torres R.D., Chaparro-Huerta V., Flores-Soto M.E., Orozco-Suárez S.A., Zárate C.B.Fuentes:scopusADAM10 in Alzheimer's disease: Pharmacological modulation by natural compounds and its role as a peripheral marker
ReviewAbstract: Alzheimer's disease (AD) represents a global burden in the economics of healthcare systems. Amyloid-Palabras claves:ADAM10, Alzheimer's disease, Natural compounds, Pharmaceutical, α-SecretaseAutores:Antoni Camins, Busquets O., Cano A., Cominetti M.R., Di Luca M., Endres K., Ettcheto M., Manzine P.R., Marcello E., Olloquequi J., Pelucchi S.Fuentes:scopusCharacterization of [<sup>3</sup>H]nisoxetine binding in rat vas deferens membranes: Modulation by sigma and PCP ligands
ArticleAbstract: Sigma (σ) and phencyclidine (PCP) receptor ligands, apart from their main effects on σ receptors andPalabras claves:Noradrenaline transporter, PCP ligands, Sigma ligands, Vas deferens, [ H]nisoxetine 3Autores:Antoni Camins, Camarasa J., Escubedo E., Gasulla D., Pallás M., Pubill D., Sureda F.X.Fuentes:scopusAssessment of the adrenergic effects of orphenadrine in rat vas deferens
ArticleAbstract: The peripheral adrenergic effects of orphenadrine, an antiparkinsonian drug, have been evaluated inPalabras claves:Autores:Antoni Camins, Camarasa J., Canudas A.M., Escubedo E., Pallás M., Pubill D., Sureda F.X.Fuentes:scopusAn overview of investigational antiapoptotic drugs with potential application for the treatment of neurodegenerative disorders
ReviewAbstract: Importance of the field: The increase in life expectancy in developed countries has given rise to sePalabras claves:Alzheimer's disease, apoptosis, Neuroprotective drugs, Parkinson's DiseaseAutores:Antoni Camins, Folch J., Junyent F., Pallás M., Sureda F.X., Verdaguer E., Zárate C.B.Fuentes:scopusAntiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases
ReviewAbstract: The purpose of this review is to discuss potential pathways involved in the pathogenesis of neurodegPalabras claves:Alzheimer's disease, apoptosis, Cyclin-dependent kinases, Glutamate receptors, Neuronal cell death, Neuroprotective drugs. apoptosis, Parkinson's DiseaseAutores:Antoni Camins, Auladell C., Canudas A.M., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Sureda F.X., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusCarnosine prevents methamphetamine-induced gliosis but not dopamine terminal loss in rats
ArticleAbstract: The neuroprotective effect of carnosine, an endogenous antioxidant, was examined against methamphetaPalabras claves:Benzodiazepine receptor, peripheral-type, Carnosine, HSP27, Methamphetamine, [ H]GBR 12935 3, [ H]Paroxetine 3Autores:Antoni Camins, Camarasa J., Escubedo E., Pallás M., Pubill D., Sureda F.X., Verdaguer E.Fuentes:scopusAging biology: A new frontier for drug discovery
ReviewAbstract: Introduction: The prevalence of age-related pathologies, such as cardiovascular disease, neurodegenePalabras claves:Autores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Verdaguer E., Zárate C.B.Fuentes:scopus