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APOE allele frequencies in suspected non-amyloid pathophysiology (SNAP) and the prodromal stages of Alzheimer’s Disease
OtherAbstract: Biomarker definitions for preclinical Alzheimer’s disease (AD) have identified individuals with neurPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleAPOE genotype modifies the association between central arterial stiffening and cognition in older adults
OtherAbstract: Arterial stiffening is associated with cognitive impairment and prodromal Alzheimer's disease. ThisPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleAPOE ε4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease
OtherAbstract: Literature suggests vascular endothelial growth factor A (VEGFA) is protective among those at highesPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleA/T/N polygenic risk score for cognitive decline in old age
OtherAbstract: INTRODUCTION We developed a novel polygenic risk score (PRS) based on the A/T/N (amyloid plaques (A)Palabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleGenetic associations with brain amyloidosis
OtherAbstract:Palabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleGenetic associations with brain amyloidosis: Genetics/genetic factors of Alzheimer's disease
OtherAbstract: Background Genetic studies of Alzheimer’s disease (AD) have focused on the clinical or pathologicalPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleGenetic interactions within inositol-related pathways are associated with longitudinal changes in ventricle size
OtherAbstract: The genetic etiology of late-onset Alzheimer’s disease (LOAD) has proven complex, involving clinicalPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleGenetic modification of the relationship between phosphorylated tau and neurodegeneration
OtherAbstract: Background A subset of individuals present at autopsy with the pathologic features of Alzheimer's diPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleGenetic resilience to amyloid related cognitive decline
OtherAbstract: Preclinical Alzheimer’s disease (AD) is characterized by amyloid deposition in the absence of overtPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleGenetic variants and functional pathways associated with resilience to Alzheimer’s disease
OtherAbstract: Approximately 30% of older adults exhibit the neuropathological features of Alzheimer’s disease withPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:google