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Cerebrospinal fluid and plasma neurofilament light relate to abnormal cognition
OtherAbstract: Introduction Neuroaxonal damage may contribute to cognitive changes preceding clinical dementia. AccPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleCerebrospinal fluid β-amyloid42 and neurofilament light relate to white matter hyperintensities
OtherAbstract: White matter hyperintensities (WMHs) are associated with poorer brain health, but their pathophysiolPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleAssessing working memory in mild cognitive impairment with serial order recall
OtherAbstract: Background: Working memory (WM) is often assessed with serial order tests such as repeating digits bPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleAssociation between common variants in RBFOX1, an RNA-binding protein, and brain amyloidosis in early and preclinical Alzheimer disease
OtherAbstract: Importance Genetic studies of Alzheimer disease have focused on the clinical or pathologic diagnosisPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleAssociations between verbal learning slope and neuroimaging markers across the cognitive aging spectrum
OtherAbstract: A symptom of mild cognitive impairment (MCI) and Alzheimer’s disease (AD) is a flat learning profilePalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleAsymptomatic Alzheimer disease: defining resilience
OtherAbstract: Objective: To define robust resilience metrics by leveraging CSF biomarkers of Alzheimer disease (ADPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleBiobank-wide association scan identifies risk factors for late-onset Alzheimer’s disease and endophenotypes
OtherAbstract: Dense genotype data and thousands of phenotypes from large biobanks, coupled with increasingly accesPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleBrain expression of the vascular endothelial growth factor gene family in cognitive aging and alzheimer’s disease
OtherAbstract: Vascular endothelial growth factor (VEGF) is associated with the clinical manifestation of AlzheimerPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleAPOE allele frequencies in suspected non-amyloid pathophysiology (SNAP) and the prodromal stages of Alzheimer’s Disease
OtherAbstract: Biomarker definitions for preclinical Alzheimer’s disease (AD) have identified individuals with neurPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleAPOE genotype modifies the association between central arterial stiffening and cognition in older adults
OtherAbstract: Arterial stiffening is associated with cognitive impairment and prodromal Alzheimer's disease. ThisPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:google