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Cerebrospinal fluid β-amyloid42 and neurofilament light relate to white matter hyperintensities
OtherAbstract: White matter hyperintensities (WMHs) are associated with poorer brain health, but their pathophysiolPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleAPOE genotype modifies the association between central arterial stiffening and cognition in older adults
OtherAbstract: Arterial stiffening is associated with cognitive impairment and prodromal Alzheimer's disease. ThisPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleAPOE ε4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease
OtherAbstract: Literature suggests vascular endothelial growth factor A (VEGFA) is protective among those at highesPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleFree-water metrics in medial temporal lobe white matter tract projections relate to longitudinal cognitive decline
OtherAbstract: Although hippocampal volume has served as a long-standing pbkp_redictor of cognitive decline, diffusPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleEvaluating Alzheimer's disease biomarkers as mediators of age-related cognitive decline
OtherAbstract: Age-related changes in cognition are partially mediated by the presence of neuropathology and neurodPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleDiscovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium
OtherAbstract: Late-onset Alzheimer disease (AD) has a complex genetic etiology, involving locus heterogeneity, polPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleNeurofilament relates to white matter microstructure in older adults
OtherAbstract: Cerebrospinal fluid (CSF) neurofilament light (NFL) is a protein biomarker of axonal injury. To studPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleInteractions between GSK3β and amyloid genes explain variance in amyloid burden
OtherAbstract: The driving theoretical framework of Alzheimer's disease (AD) has been built around the amyloid-β (APalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:googleStroke risk interacts with Alzheimer's disease biomarkers on brain aging outcomes
OtherAbstract: Alzheimer's disease (AD) biomarkers and stroke risk factors independently pbkp_redict cognitive impaPalabras claves:Autores:Jefferson Michael Acosta OrtizFuentes:google