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Biotecnología(3)
Multiple gene copy number enhances insulin precursor secretion in the yeast Pichia pastoris
ArticleAbstract: We have found a direct relationship between protein production in Pichia pastoris and the number ofPalabras claves:Insulin, Multiple gene copies, PICHIA PASTORIS, Protein expressionAutores:Besada-Pérez V., Cabello C., Castellanos L.R., García L., Hernández L., Hidalgo A., José-Manuel Pais-Chanfrau, Lamazares E., Mansur M., Martinez E., Plana L., Terrero Y., Valdés J., Varas L.Fuentes:googlescopusImproving the expression of mini-proinsulin in Pichia pastoris
ArticleAbstract: Increased expression of recombinant mini-proinsulin in Pichia pastoris in 2.5 l bioreactors was achiPalabras claves:AOX promoter, fed-batch culture, PICHIA PASTORIS, Recombinant human insulinAutores:Besada-Pérez V., Cabello C., Castellanos‐Serra L., Del C. Abrahantes-Pérez M., Del Toro Y., García Y., Hernández L., Hidalgo A., José-Manuel Pais-Chanfrau, Licor L., Mansur M., Martinez E., Plana L., Támbara Y., Valdés J.Fuentes:googlescopusModeling of mini-proinsulin production in Pichia pastoris using the AOX promoter
ArticleAbstract: An unstructured model based on mass balance equations for a recombinant methylotrophic yeast PichiaPalabras claves:fed-batch culture, Fermentation, Modeling, PICHIA PASTORIS, Recombinant human insulinAutores:Cabello C., José-Manuel Pais-Chanfrau, Mansur M., Rodríguez L., Valdés J., Varas L.Fuentes:googlescopus